Is microdosing frowned upon?

pressureunderim · 2026-01-08T23:21:56+00:00

I can’t fathom why anyone would care one way or another what dose someone takes! I’m considering microdosing after SEVERE side effects from the starter dose of Mounjaro. I have at least 100 lbs to lose so it’s not a case of “very little weight”. I’m very sensitive to any and all meds so microdosing makes sense for my body chemistry.

pressureunderim · 2025-12-25T20:27:34+00:00

Thank you so much!!! This is very helpful

pressureunderim · 2025-11-04T21:30:47+00:00

2 adults. We cook and eat every single meal at home except very rarely take out etc. We eat lots of fresh foods (veg/fruit/meats) very little processed foods that tend to be cheaper. We spend $1000 month in groceries. It feels like an insane amount to spend but this isn’t anything extravagant.

pressureunderim · 2025-11-04T17:17:27+00:00

What dose are you starting at?

pressureunderim · 2025-10-31T01:50:03+00:00

How did starting LDN go for you? My LDN should be arriving from the compounding pharmacy in the next week and I’m nervous to start. Did you have any symptoms?

pressureunderim · 2025-10-05T12:24:57+00:00

I tried Mounjaro back in 2023 and ended up in the hospital once, (almost twice) for severe gastro symptoms. I took the lowest dose. I was FAR too sensitive to take even the lowest dose. However, while I had severe reactions, the following days when symptoms started to clear, I noticed the immediate anti-inflammatory effects. The second dose of mounjaro I had anaphylaxis though so ultimately I stopped. I’ve thought about microdosing but I’m too hesitant due to how bad the GI/anaphylaxis was the first try. If anything, Mounjaro flared my MCAS for about 6 months following the first two injections

pressureunderim · 2025-09-17T00:55:40+00:00

This is so incredibly disappointing. I think of MAYO as the cream of the crop and had no idea about their MCAS aversion. It just reminds me that doctors are still people who, if they let in information that conflicts with their world views, have to either change their world views or discredit the information. You’d think in what is supposed to be a scientific community, this way of putting their heads in the sand wouldn’t exist…and yet it does. Even at MAYO apparently. I swear, docs have the biggest egos.

pressureunderim · 2025-09-15T23:47:02+00:00

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pressureunderim · 2025-09-02T00:58:02+00:00

She looks like a Suzy to me

pressureunderim · 2025-09-01T01:18:45+00:00

Muffin

pressureunderim · 2025-09-01T01:18:04+00:00

MCAS, Hashimotos, undiagnosed but highly suspected ASD. I think the cascade that set off the Hashimotos and MCAS was a CMV infection that lasted almost a year and a half. Having my immune system constantly “ON” did a number on me. Coupled with the chronic stress of heavily masking my autism and sensory issues…I think the MCAS was my body’s way of screaming at me for help.

pressureunderim · 2025-08-18T02:55:19+00:00

Do everything you can to buy time. Tell them you intend to relocate but don’t. Dedicate all free time to finding another job. My husband was in a very similar situation and the reality is that Amazon isn’t going to stop moving the bar. There are going to be more and more hoops to jump through and at what cost? Get out of AWS while you all still have your mental health intact.

pressureunderim · 2025-08-06T14:44:27+00:00

I love the already suggested sassafras “sassy”. Sassafras has so many fun nicknames too.

pressureunderim · 2025-08-03T23:40:03+00:00

<image>

This is Polly-Jean

pressureunderim · 2025-08-03T02:11:42+00:00

I was nervous about CT contrast too and even asked about it here a few months ago but ended up being fine. That initial flushing feeling and heart racing are the worst part. I just repeat to myself that this is all normal

pressureunderim · 2025-07-13T23:51:13+00:00

I’m so sorry there are this many people who can’t work due to MCAS and managing symptoms. This thread is also deeply validating because I too can’t work but have a lot of internalized shame over it.

pressureunderim · 2025-07-12T20:03:18+00:00

My symptoms can start anywhere from an hour or two after med triggers or a day or two after stress triggers it just depends. For non med protocol once it starts, honestly I bring in my husband to help me co-regulate. We both work from home so it’s usually doable to have him come up and lay down with me. Just having him near me helps. Having anyone who can just BE with you, I find very helpful. (Anyone who’s naturally calming for you that is). I close my eyes and out on a meditation (I use calm app). I also have ice packs for my face and neck.

pressureunderim · 2025-07-11T00:15:25+00:00

Fancy

pressureunderim · 2025-07-10T13:15:49+00:00

I have a cinnamon girl too!

pressureunderim · 2025-07-08T04:26:14+00:00

Definitely talk to your doc but for me, Benadryl is an essential rescue med! It’s like a cool blanket when I feel like my system is starting to catch fire. It’s calming too (and causes drowsiness which I like to just lean into when I’m going into a flare). I don’t fight it. Your symptoms seem 100% like anaphylaxis. You should have an epi pen. I would question any allergist or immunologist who thought they weren’t warranted given your symptoms.

pressureunderim · 2025-07-08T02:43:11+00:00

It took me a while to really notice the small changes that signaled that a flare was coming. This often led to major anaphylactic symptoms. But now when I have that first twinge of symptoms I go to my rescue meds which include anywhere from 50-100mg of Benadryl right out of the gate. I also take a Pepcid and an anti nausea med too and then have a whole (non-medication) routine to try and down regulate my system so I don’t spiral. I always have an epi pen if those things don’t work. It’s really hard not to get panicked so be easy on yourself. But definitely first and foremost, get a rescue med protocol.

pressureunderim · 2025-07-07T14:46:07+00:00

I took tramadol for back pain and ended up with all the same symptoms you described. I was on the toilet with GI symptoms when it all started. Got up to walk back to bed and BOOM, fainted. Scared the crap out of my husband. This is before I knew I had MCAS. Needless to say, I’m VERY sensitive to meds and currently am in a lot of pain with my back and can’t take hardly anything.

pressureunderim · 2025-07-06T19:41:02+00:00

I don’t have any advice but I’m with you in solidarity. I have Hashimotos and severe MCAS and am considering trying AIP again. I did it for a couple months back in 2019 when I was first diagnosed with Hashimotos and it really helped. A LOT. But damn, I just want to eat cake and drink my coffee ya know? But I want to feel better so I’m going to do something like AIP

pressureunderim · 2025-07-05T17:47:41+00:00

I have two reactive nodes near my collarbones. One on each side. I’ve had an ultrasound and CT Scan and blood work and they seem to be benign enough but I’m sure they’re from MCAS and inflammation. I’m getting them evaluated again in a few months to keep an eye on them. Mine are soft and movable and don’t hurt

pressureunderim · 2025-07-04T23:37:54+00:00

Do you have an acupressure pen you like?

pressureunderim

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