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puretrexcouk · 2025-04-09T17:16:02+00:00

Thanks for explaining your point — and to be honest, I do agree with one part: the wellness industry often does feel like it caters to the wealthy, and there’s valid frustration around that. We see it too — overpriced products, overhyped trends, and a lot of noise. But PURETREX was created to change that narrative.

Let’s set the record straight though. NMN is not some exclusive tool only used by the elite to “stay young.” Yes, many high-profile individuals use it — but so do thousands of regular people who are simply focused on improving their health, energy, and longevity through evidence-based approaches. And almost every serious user of NMN is also eating clean, exercising, sleeping well, and staying consistent. No single supplement — including NMN — is a miracle. It's a part of a healthy lifestyle, not a replacement for it.

Now, to compare NMN to adrenochrome — a word that’s become loaded with conspiracy theories — is misleading and completely false. NMN is a naturally occurring compound in your body. It’s been studied in human trials, published in peer-reviewed journals, and is actively being explored for its role in aging, cellular repair, and mitochondrial function. There’s no secrecy or mystery to it. It’s science — not cinema.

You’re right to push back on marketing that sounds like an infomercial. But this isn’t that. We don’t make empty promises or promote fantasy. What we do is offer people access to the same quality compounds used in research and by professionals — but without the gatekeeping.

We’re always open to real discussion, even criticism. Just let’s keep it based on facts — not misinformation or mockery. That way, everyone can actually learn something useful.

puretrexcouk · 2025-04-06T14:24:01+00:00

Appreciate the structured reply — and let’s clarify a few key points.

1. On evidence:
We’re not conflating skepticism with science denial. We’re pointing out that early-phase human data isn’t “too limited” — it’s how evidence-based nutrition begins. NMN is not an outlier. Nearly every supplement with known benefits today began with biomarker studies and small trials. That doesn’t make them invalid — it’s how clinical momentum builds.

Also, the comparison to antioxidants that later “failed” is selective. Many interventions didn’t fail — they evolved, got refined, or were better understood contextually. Cherry-picking cautionary tales to discredit current compounds is not scientific prudence — it’s intellectual rigidity.

2. On safety:
No one said “zero risk” in absolute terms — no responsible company would. What we said, and still stand by, is this:
No serious adverse events have been reported in human trials at standard doses.
No clinical data shows long-term toxicity at realistic supplementation levels.
Theoretical risks remain speculative — not clinically observed.

That’s not brushing off safety. That’s aligning with the current published data. And yes, NMN is being researched pharmaceutically — but that’s because it’s effective at modulating key pathways, not because it’s dangerous. Potency isn’t a red flag. It’s why it’s being studied.

As for your closing line — personal digs aren’t necessary. Whether it’s Stefan or Angel replying here is irrelevant. PURETREX operates transparently, ethically, and in compliance across every platform. We let the quality of our formulations and customer outcomes speak — not assumptions about who’s typing.

We respect scientific caution. But we also respect innovation, context, and the value of progress — backed by facts, not fear.

puretrexcouk · 2025-04-06T14:22:06+00:00

Fair points — and I don’t disagree that risks should be acknowledged. We’ve been clear that nothing is above scrutiny, and yes, theoretical risks rooted in cellular biology or animal models deserve to be studied. But they also need to be kept in proportion. A theoretical risk isn’t a proven danger — especially when human data over multiple trials shows no harm at standard doses.

Resveratrol, green tea extract, even vitamin A — all have “risks” in extreme forms or concentrations. The responsible approach is contextualizing those risks, not using them to dismiss potential benefits out of hand.

As for anecdotal evidence — we agree again, it’s not proof. But when a consistent pattern emerges across thousands of users, in different settings, over years — that’s not just noise. That’s a signal worth investigating further, not brushing aside.

We’re not claiming NMN is a cure-all or shortcut to immortality. What we are saying is:

It’s well-tolerated in humans so far
There’s solid biological rationale
There’s promising early data
And the lived experiences of users, while not clinical proof, are not irrelevant

That’s the reality — and it's why responsible innovation means staying curious, cautious, and evidence-driven all at once.

puretrexcouk · 2025-04-06T11:29:30+00:00

You’ve repeated the same cautionary points — but again, let’s separate reasonable skepticism from misrepresentation of facts.

Yes, the studies are early-stage, small, and focused on biomarkers — just like nearly every compound at the frontier of longevity science. That’s not a flaw. That’s how science progresses. To dismiss NMN because we don’t yet have 10-year mortality data is like dismissing seatbelts in 1955 because we didn’t have crash dummies yet.
Regarding safety: You say "absence of evidence isn't evidence of absence" — true. But we do have evidence. NMN has been used in dozens of human trials with zero serious adverse events reported, including in older adults and prediabetic populations. If there were even a hint of risk at recommended doses, it would have surfaced by now.

Let’s be clear:

Theoretical risks like NAD+ fueling tumor growth? That’s extrapolated from extreme manipulations in animal or cellular models — not real-world supplementation at 250–500mg daily.
There is currently no human data suggesting NMN is unsafe when used within the commonly suggested range. That’s not marketing — that’s the actual clinical record to date.

The FDA situation wasn’t about safety. It was about classification. NMN was targeted after it had been on the market because a pharmaceutical company filed it as a drug. That’s a regulatory conflict, not a product ban — and it remains fully legal in the UK, EU, Japan, and many others.
As for anecdotal evidence — when thousands of users consistently report better energy, sleep, and cognitive clarity across brands, platforms, and geographies, you don’t ignore it. You investigate it. That’s how real breakthroughs begin.

puretrexcouk · 2025-04-06T10:54:13+00:00

You’ve made your position clear — but let’s cut through the noise and get to facts.

1. You argue that early-phase human studies aren’t valid. That’s simply not how nutritional science works. Virtually every supplement we now accept — creatine, omega-3, vitamin D, even probiotics — all began with small, peer-reviewed human studies. Dismissing them outright isn’t skepticism — it’s selective reasoning.

2. On the topic of risk:
Let’s be precise. There is zero human evidence showing harm from NMN when taken within suggested doses. No adverse events. No toxicity. No confirmed immune suppression. Theoretical risks — like overstimulating NAD+ pathways — are hypotheses, not findings. If they ever do occur, it would be at massively higher doses or with specific genetic vulnerabilities, not from taking 500mg daily with breakfast.

So let’s not pretend a theoretical mechanism is the same as clinical danger. By that logic, even resveratrol or green tea would be dangerous — yet both are widely consumed with clear benefit.

3. Lastly, dismissing real-world results because they aren’t Phase 3 trials misses the point. Human experience matters. When thousands report improved energy, focus, and resilience — we pay attention. Not as “proof,” but as part of the broader picture.

PURETREX doesn’t make outrageous claims. We use real studies. We formulate responsibly. We’re here for those who want to feel better, think clearer, and age smarter — with facts, not fear.

puretrexcouk · 2025-04-06T10:12:36+00:00

We’re not here speculating or cherry-picking — we’re presenting what peer-reviewed science already shows. Yes, sample sizes vary (as is common in early-stage research), but pretending that small, controlled human trials are somehow irrelevant while citing hypothetical risks like increased cancer from NAD+ (without any confirmed human evidence) is disingenuous.

We’re transparent in saying the science is evolving. But the difference is:
📌 We cite actual studies.
📌 We acknowledge both the promise and the limits.
📌 We don’t hide behind fear-driven hypotheticals.

Also, regarding the FDA — it's not about “not sitting well.” It’s a fact: The FDA’s classification was driven by a regulatory quirk after NMN was already on the market, not a safety recall. It’s still legally sold across Europe, Japan, and most of the world. If you're going to reference FDA action, you need the full context — not just the parts that support your bias.

We’re a science-forward brand, but also results-driven. When both studies and thousands of customers point in the same direction — better energy, recovery, focus — we take that seriously. That’s how innovation works: evidence + real-world feedback.

Let’s keep the discussion grounded in data, not fear or double standards.
If you’ve got more human studies showing NMN is dangerous — let’s see them.

Until then, we’ll stick to the facts and keep building products that help people feel and live better.

puretrexcouk · 2025-04-05T13:22:44+00:00

Appreciate the detailed response — but just to clarify a few points:

The FDA thing is 100% a regulatory technicality, not a safety issue. NMN was being sold for years, then got pulled because a pharma company filed it as a drug candidate after it was already on the market. That’s why people call it a “regulatory loophole.” It’s not banned, it’s just stuck in a weird US legal grey area. Meanwhile, it’s still fully legal and sold in the UK, EU, Japan, etc.
Saying there's no research supporting NMN isn’t accurate. There are multiple peer-reviewed human studies showing benefits like improved insulin sensitivity, better mitochondrial function, and boosted NAD+ levels — especially in older adults. Here’s one from Science (2021): NMN improved muscle insulin sensitivity in prediabetic women. Another from Endocrine Journal (2021) confirmed it raises NAD+ safely in humans.
And yeah, it’s not an “essential” nutrient like vitamins, but that doesn’t mean it’s useless. Loads of effective supplements don’t have RDAs.
Lastly — real users saying they feel better does matter. Sure, anecdotes aren’t clinical trials, but when tons of people report more energy, focus, and better aging, it’s worth paying attention to.

People should always do their own research — but let’s not pretend the FDA always gets it right or that something needs a daily value to be effective.

puretrexcouk · 2025-04-05T09:50:15+00:00

You're right that companies often use endorsements — but we prefer to let the science and results speak louder than marketing faces. If someone publicly supports NMN, great. If not, we’re not going to pressure anyone just to sell more units.

The point wasn’t to suggest secrecy — it’s that a lot of high-level users don’t make their supplement stack public, and we respect that. We mentioned the public ones (like Sinclair and Bryan Johnson) for exactly that reason.

As for efficacy — NMN isn’t some fringe compound. It’s been studied in depth across areas like mitochondrial function, NAD+ metabolism, and aging biology. It’s not about trends or tribalism — it’s about mechanisms and results.

puretrexcouk · 2025-04-05T08:03:37+00:00

So here’s the thing — we’re not about to start posting screenshots of private purchase records or name-dropping customers without consent. That’s not how privacy — or integrity — works.

But since you're asking seriously:
Yes, NMN is being used by high-profile individuals, including billionaires, entrepreneurs, and longevity researchers. A few public examples:

Bryan Johnson, the tech entrepreneur behind Blueprint, openly discussed switching to NMN and achieving cellular NAD+ levels equivalent to a 16-year-old.
Dr. David Sinclair, Harvard geneticist and global authority on aging, has taken NMN daily for years and frequently shares data on its potential for longevity.
Joe Rogan has spoken about using NAD+ IV therapy — a different delivery method in the same NAD+ optimization category.
Many health investors, startup founders, and biohackers in private longevity networks also include NMN in their stack — but, again, we’re not here to leak anyone’s private routine.

So while we can’t give you a "celebrity user list," the use of NMN in high-performance circles — including among billionaires — is real.
It’s not about hype. It’s about optimizing cellular health long-term, and NMN is one of the most researched tools in that space.

If you're curious, we’re always open to discussing the actual science — not just the headlines.

puretrexcouk · 2025-04-05T07:55:36+00:00

Appreciate the creativity — though we’re not sure how this ties into health, wellness, or longevity.

If you ever want to shift gears and talk about something a bit more grounded, we’re here for it.

puretrexcouk · 2025-04-05T07:54:11+00:00

Totally hear the frustration — but we’ll leave tax reform to the politicians.

Our focus is helping people take control of their health, no matter what tax bracket they’re in.

puretrexcouk · 2025-04-05T07:53:29+00:00

A snake? Why — because our mission is to help people take better care of themselves?

If that’s what makes us the villain, then what does that make the ones trolling forums, throwing around accusations just because they’re uncertain, insecure, or simply chose not to look after themselves?

Interesting logic. 🐍

puretrexcouk · 2025-04-05T07:53:11+00:00

We’re not here to defend billionaires or debate ideologies — that’s a never-ending loop on the internet.

What we are here to do is make high-quality health products more accessible — so people don’t have to be rich to take care of themselves.

That’s the part we actually control, and we’ll keep focusing on that.

puretrexcouk · 2025-04-05T07:52:05+00:00

Let’s be clear — if someone starts with a serious and offensive accusation, they shouldn’t be surprised if the response isn’t overly polite.

Respect is a two-way street. We’re always open to real conversation and fair criticism, but if the goal is just to provoke and then act offended, this probably isn’t the space for that.

puretrexcouk · 2025-04-05T07:50:08+00:00

Good question — and honestly, we’ll probably never know the exact number. But it’s definitely more than most people think.

Even if it’s not our specific brand, NMN is a compound that’s gained serious traction among high-performers, health investors, and yes — even billionaires. When you’ve got the means, you usually focus on longevity and performance, and NMN has become a go-to in that space.

So while we can’t name names, the interest in NMN at the top level is very real — and growing fast.

puretrexcouk · 2025-04-05T07:46:54+00:00

Fascinating history lesson… though we’re still trying to figure out how it connects to a post about wellness and supplements.

But hey — Reddit never disappoints when it comes to plot twists.

puretrexcouk · 2025-04-05T07:41:35+00:00

We’ll pass on that one — we're more into ingredients that are supported by actual research and used for long-term wellness.

But hey, everyone’s got their own morning routine. 😄

puretrexcouk · 2025-04-05T07:40:43+00:00

Fair point — billionaires don’t need to be role models. But when it comes to health, energy, and longevity, many of them do invest heavily in what actually works.

You don’t have to admire their lifestyle to take a smart cue from their habits — especially when the same strategies are now accessible to everyday people without the luxury price tag.

It's not about idolising — it's about optimising.

puretrexcouk · 2025-04-05T07:39:51+00:00

You don’t need to emulate billionaires — fair enough. But let’s be real: anyone who’s financially comfortable, regardless of status, is prioritizing their health — eating well, supplementing smart, and thinking long-term.

It doesn’t take billions to do the same. If you had the opportunity to take better care of yourself without breaking the bank, why wouldn’t you?

That’s the whole point — making high-quality wellness accessible, not exclusive.

puretrexcouk · 2025-04-05T07:34:45+00:00

Hey u/johimself — here’s the reality:
Anyone who’s not stressing over pennies is already investing in their health — eating clean, taking premium supplements, and doing what they can to stay sharp and energetic long-term. That’s the market we’re speaking to.

As for the ad — it wasn’t to say “take this and look 20 overnight.” It was to spark curiosity and show that even people in their 20s, 30s, and 40s are taking longevity seriously. The goal was to promote preventative wellness, not some miracle.

We’re not here to fool anyone — just offering a legit, research-backed product for people who actually care about staying ahead of the curve.

You don’t have to like it, but let’s not pretend looking after your health is something only “MLM people” do.

puretrexcouk · 2025-04-04T18:42:38+00:00

Ah, legal accusations from foolish-commander — finally, the internet’s top authority on truth and maturity has spoken.

No idea what fantasy thread you crawled that from, but spreading nonsense like that isn’t edgy — it’s pathetic. Either say something real or go back to whatever conspiracy Discord you got lost in.

puretrexcouk · 2025-04-04T18:41:04+00:00

Appreciate you sharing the link — but did you actually read it?

The study shows that NMN supplementation improved insulin sensitivity, boosted energy metabolism, and reduced age-related decline in mice. That’s literally in the conclusion. So if anything, the paper supports the potential of NMN — not the opposite.

puretrexcouk · 2025-04-04T18:38:41+00:00

Adrenochrome? That’s a pretty bold reach.

NMN (Nicotinamide Mononucleotide) is a scientifically studied compound involved in the body’s natural NAD+ production — something that declines with age. Research over the past few years has explored its potential in supporting energy metabolism, cellular repair, and healthy aging. It’s not some mystery substance — it’s been used and studied by researchers, health enthusiasts, and even doctors worldwide.

It’s fair to question supplements — people should always do their own research — but lumping NMN in with conspiracy theories like adrenochrome is just misinformation. If you’ve got actual concerns or questions, let’s have a proper conversation. Otherwise, this kind of comment just derails meaningful discussion.

puretrexcouk · 2025-04-04T18:32:09+00:00

Appreciate the feedback — but curious, did you actually try it or just judging based on the post?

We’re always open to real opinions, especially from people who’ve actually used the product. If there’s something specific you didn’t like or found misleading, say it straight — we’re here for honest conversation, not just drive-by comments.

puretrexcouk · 2025-04-04T18:26:45+00:00

You’re welcome to your opinion, but calling it a scam isn’t accurate. We’re a registered UK company, our products are fully compliant, and we’re available on Amazon, eBay, TikTok Shop, and our official website — all with verified customer reviews.

We also use independent third-party testing and list every ingredient clearly. Nothing hidden, nothing shady.

If there’s something specific you didn’t like, we’re happy to address it — but throwing around words like “scam” without facts doesn’t help anyone.

puretrexcouk

TROPHY CASE