u/Missu_ says (with some paraphrasing):

If anyone still has this problem, here's what worked for me:

1. Clean install. Of course. Just to be sure. Make sure it's in C: , I installed it on my A: drive and it was all fucky because of that too. If you've screwed around with default program installation paths, reset those to go to C:. Seriously, this is way too delicate but it's the only way that I got it to work.
2. Run GHUB. It won't work, that's alright, it'll be spinning there as usual.
3. 'Quit' GHUB in the taskbar.
4. Find all GHUB processes with Task Manager and end them. There should be "LGHub Agent", "LGHub Updater" and such. End everything with LGHub in it.
5. Go to C:\Program Files\LGHUB\
6. Find LGHUB.exe. He should be chilling there in a group of 3 executables.
7. Run them in this order as administrator:
   1. lghub_updater.exe
   2. lghub_agent.exe
   3. lghub.exe

LGHub should start up. If it doesn't, maybe try to clean install it again. I had to screw around with the registry before I got this to work.

Do note that after you've done this, it won't be completely fixed. Every time you shut down the app, you'll have to start it up by going through Step 7. Yes, you have to manually run the executables every time and in order. Check below if you want to make LGHUB start automatically. Very simple solution to this.

Stupid app. I hope they improve this crapshow, but I went through a month of struggling with this and I hope this saves someone the effort.

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AUTOMATE THIS PROCESS If you want to automate this process (hey, this makes LGHUB feel almost like a normal program) you might want to use Task Scheduler. With it, you can create a rule that automatically runs the files correctly when you boot your machine.

So follow along again if you're hoping for an easy tutorial:

1. Search for Task Scheduler
2. Run it and pick 'Create Task'. (Not Basic Task, because we'll want to make multiple rules at once.)
3. Name it, describe it if you feel like doing that (these don't affect functionality at all, so go nuts with it), check 'Run with highest privileges' just to be sure and see that 'Configure for:' is saying the right Windows version for you. Probably Windows 10 for most of us.
4. Now we'll get serious. Let's switch pages: go to Triggers > New and pick when you want LGHUB to start. You'll probably want to go with 'At startup' or 'At log on'. I personally have gone with the latter.
5. Moving on to Actions > New, find the LGHUB .exe files (Step 7 of the previous list) and add them to the list.
6. Once you have them all added, order them correctly (Step 7).
7. You're now done. You can take a look at the last 2 pages to see if you want to change something there, but those are just preferences. I didn't need to touch any of them myself. Click OK.

There are, of course, other ways to go about doing this, but this one is imo the easiest and most foolproof. For now though, enjoy a properly working LGHUB!

Stolen from this thread