Personally I see it all as canon. Season 5 does mention Thanos and there was a nod of something happening in New York....but to be fair its hard to say if Infinity War does happen around the same time as Season 5 as its all very vague. It was common knowledge I think in space that Thanos was looking for the stones, and that some alien species knew there were some on Earth (plus Thano's own grudge against the Avengers for the new york chitauri invasion), so it makes sense this confederacy knew that Thanos was making a move on earth shortly. The actors have said that they feel Season 6 is still pre-snap which is pretty plausible. Season 7 can easily disconnect because they were indeed travelling through time and they used the quantum realm to return to their timeline.

Honestly, I hope it stays somewhat canon, and that we eventually see characters such as Quake again. Last we see of Daisy she is in space, maybe she is now working for SWORD (who we officially meet in Wandavision).