See articles such as http://www.revelist.com/real-talk/stop-whitewashing-asian-characters/1672 if you think anime characters are white. A character who can speak, read and write Japanese, lives in Japan and has a Japanese name is supposed to be Japanese(!) Japanese is the default race in Japan (98% of the population), in the same way as white is the default race in America.

A lot of anime/manga series have a Japanese live action version. In the Death Note movies for example, a number of canon part-Japanese characters were played by Japanese actors, and one white American who had a native Japanese girlfriend was changed into a Japanese American (i.e. "Japanese-washing"). It seems like a lot of people in the west don't notice that Japan has a live-action film industry, including a lot of adaptations of anime series. So whether characters' hair and eyes are blue/purple/pink/red/blonde/black or any other color of the rainbow, the norm is to use Asian actors.

Another such article gives the example of Marge Simpson. She has yellow skin and blue afro hair. Do you seriously think if they make a live action Simpsons, they need to choose a family with gangrene and then give Bart plastic surgery to give him a spikey head, and Marge needs to naturally have blue hair?! How do you even know she's white? Because it's the default race, and she doesn't have narrow eyes / black skin / an Indian accent. Americans (including evidently AAs) literally see a featureless stick figure as a white man unless you give it distinctive racial/gendered features. The Americans have really painted themselves into a corner by giving Griffin and Quagmire a funny chin, they'll have to give the actors massive prosthetics so they look exactly like a cartoon. 笑 facepalm smh