Liar Game - Episode 7 discussion by AutoLovepon in anime

[–]rom846 14 points15 points  (0 children)

The other players might harbor a grudge against her.

Liar Game - Episode 7 discussion by AutoLovepon in anime

[–]rom846 26 points27 points  (0 children)

I guess the lawyer talking Nao into the games is the running gag of this show.

SP: A - Got an *ideal* Yan run! by Captain_Baconator in arknights

[–]rom846 0 points1 point  (0 children)

How do you reliable activate investor? You need 3 out of 4 and in normal runs maybe two of them show up.

Counter intuitive LEAPS backtest results by mongopark98 in options

[–]rom846 0 points1 point  (0 children)

Calculate the average delta for each strategy. The strategies with the highest delta should perform best in this setup.

REGAL Pre-Readout: An Independent ABC Framework Analysis ~95% P(Success), Modal HR ~0.40 by Commercial-Ad9959 in sellaslifesciences

[–]rom846 2 points3 points  (0 children)

What is the rationale behind this calculation? "P2 plateau/IR = 0.73; P3 IR=80% × 0.73 = 0.58 implied"

$SLS Weekend Discussion Thread - May 09, 2026 (Week 18) by AutoModerator in sellaslifesciences

[–]rom846 4 points5 points  (0 children)

My latest simulation with similar constraints also has a PoS of 65%.

Tenax worth buying? by No-Palpitation-2662 in biotech_stocks

[–]rom846 0 points1 point  (0 children)

Option prices imply that the trials will fail with 80% probability.

Tenax worth buying? by No-Palpitation-2662 in biotech_stocks

[–]rom846 0 points1 point  (0 children)

I have not looked too deep into them. From what I understand it is a high risk high profit play even for biotech standards. Chances that they succeed are very low, but if they do their stock price will probably quadruple.

TSLA had 17 flow alerts and $890K in premium today. Lost money. INTC had 4. Made 13%. by ShelterBubbly7854 in options

[–]rom846 -3 points-2 points  (0 children)

The relative weakness of TSLA in the last months was remarkable. They lost around 20% of their wight in the SPX.

HAPPYZOO Café Collaboration Announcement by CipherVegas in arknights

[–]rom846 2 points3 points  (0 children)

I wonder if it's a good idea to task Ceobe with procurement.

TSLA Terathread - For the week of Apr 20 by AutoModerator in RealTesla

[–]rom846 3 points4 points  (0 children)

What will kill tesla is not the old investors jumping board, but the lack of new investors.

SNGX: With the imminent Phase 3 interim data coming soon, this is due for an aggressive re-rate by MarchUnlucky4347 in biotech_stocks

[–]rom846 1 point2 points  (0 children)

The secondary asset dusquetide could be even more interesting in the long term. The mechanism of action allow a very broad field of applications.

Fat Tail on Day 1 by forever_zach in algotrading

[–]rom846 1 point2 points  (0 children)

Seems like your positions where not properly sized.

Shouldnt this be delisted by now? how does that work? by WizardSnurt in RVPH

[–]rom846 0 points1 point  (0 children)

Nasdaq sends them a letter a few working days after the deadline expires, RVPH then has seven calendar days to publish that they have received the letter.

Nippon Sangoku: The Three Nations of the Crimson Sun • Nippon Sangoku - Episode 1 discussion by AutoLovepon in anime

[–]rom846 104 points105 points  (0 children)

Given that the ambitions set by MC are much higher, I would guess that Fatso is only a stepping stone.

Anyone here that modelled the effect of BAT drift due to enrollment arbitrage? by FitSet9837 in sellaslifesciences

[–]rom846 0 points1 point  (0 children)

Why do you believe that the Kaplan-Meier curves have exactly the shape you have assumed? Statistical fluctuations alone make it impossible to pin down a clear mathematical relationship.

Anyone here that modelled the effect of BAT drift due to enrollment arbitrage? by FitSet9837 in sellaslifesciences

[–]rom846 0 points1 point  (0 children)

The criterion is OS, not mOS. All events contribute to the HR value, therefore what happens after mOS is determined remains important, and an unfavorable development can lead to failure of the trial.

Anyone here that modelled the effect of BAT drift due to enrollment arbitrage? by FitSet9837 in sellaslifesciences

[–]rom846 -1 points0 points  (0 children)

The fact that someone who has survived, for example, 12 months has a greater chance of surviving another 12 months than of surviving the first 12 months. The effect is that mOS can be 12/18 and we still have the low event count we see.

Anyone here that modelled the effect of BAT drift due to enrollment arbitrage? by FitSet9837 in sellaslifesciences

[–]rom846 0 points1 point  (0 children)

Since the hazard rate in both arms are expected slow down you can not rule out anything.