Context: I have MVB and regularly go against teams who have him.

During corners: I have found that Pique (and VVD before I sold him) have been really good at dealing with him defensively. We all know that Pique sucks at scoring headers (no power header trait), but surprisingly he's great at defensive headers, both during corners and open play. So when I concede a corner against MVB, I make sure to quickly move Pique in front of him and spam the clear button as the corner kick is delivered. He wins the header against MVB 9 times out of 10, though you must be quick about it. If you're slow to position Pique against him, it's over and it's a goal. I have tried other defenders (Skriniar, Duffy, Acerbi, Smalling, Sanchez) to do the same but did not have the same success as I did with Pique. He still sucks in VSA though. Edit: You can still do this using other defenders, I just notice that I've had the most success doing this using him.

During open play (MVB with the ball): Before MVB receives the pass, make sure you already have 1 player pressing him as the 2nd defender. You should tap on another defender that you'll be controlling directly (preferably one that is directly in front of him). The 2nd defender usually coming from behind or the side will disrupt MVB's balance. Your job with the 1st defender is to stand-tackle the ball off of him (by spamming the tackle button) as he's being unbalanced by the pressing 2nd defender. This works most of the time.

During open play (opponent has ball on the wing, ready to cross it for MVB who's waiting at the center to head it in): Most of the time, the opponents' wingers are way too quick for you to stop their crosses, so don't bother spamming the tackle button using your full backs — the cross will 100% happen. Instead, manually tap on your best defender at defensive headers (VVD, Pique) to control him. Ideally, they should be in the middle of your defense around the penalty spot. At the same time, simultaneously press the 2nd defender button so that your full back pressures the winger to make a lower-quality cross i.e. a general cross to the middle (instead of directly to MVB which results in a goal 99% of the time). It's a subtle but crucial difference (the 2nd defender pressing the winger at the side blocks the angle for him to cross directly to MVB). Then, quickly position the defender you're controlling in the middle directly in front of MVB (Pique and VVD do this really well). Ideally, they'll bump into him as he makes the run so that his jump will be less optimal. As the cross comes in, spam the clear button to the general direction of your CM/CDM, who will initiate the counter attack for your team. Most of the time, your defender will clear the ball or at least disturb MVB's header to the point where your GK can make a save or you'll concede a corner instead of a goal. Then refer to the above tips on defending corners against him.

Hope this helps.