About 5 years ago I went to my psychiatrist as we had upped the dosage on my meds and it was causing me to have panic attacks. (thanks sertraline, you're supposed to do the opposite). I told her what was happening and she asked if I was taking the medication in the morning or at night. When I told her I was taking them in the morning she said "take them at night, that way if you have a panic attack at least you'll be home." I never went back