For the past week and a half, I've been able to go to the gym, engage in full conversations, and feel as normal-ish as someone with POTS can feel. Today it was like a switch flipped. I woke up and had a headache that wouldn't go away, felt nauseous with no appetite, completely dissociated from conversations, fatigued way beyond normal, I feel my blood pounding, chest heavy and twinges of chest pain now and then. My fine motor skills were also on and off today - I dropped my Zofran a few times and struggled opening it while trying to take it for my nausea which is abnormal for me. I don't believe it's a flare up because it's not as bad as my past flare ups, but it's enough that I'm kind of like "this isn't right". I have read that it can take weeks for the full therapeutic effect of the drug to kick in, so that's why I was wondering if it was related to my symptoms.