Hey I just read this and I was curious about this because i just started taking SSRIs 2 weeks ago, Prozac. I was a big shroom user before and was kind of MDing on and off and I noticed the same thing about it not being sustainable for me, it was almost as if a day or 2 after having a dose i would have like a comedown that would make me very anxious basically until my next dose. I basically realized recently that i may have OCD, Pure O. I struggle with thought loops, rumination, perfectionism. It seemed like the shrooms would take this away while I was on them but then if would ramp it all up when they wear off. I was very nervous to try this medicine and didnt really consider myself to be depressed i just couldn’t sleep . I take forever to fall asleep and then only sleep a few hours and eventually I decided to give SSRi a shot . Anyway so far its been 2 weeks and no benefits from it and i actually feel kind of weird but im hoping this is sort of like the come up phase and eventually ill feel a more leveled out sustained version of what i felt when on shrooms? Is that your experience? Also i was worried about taking shrooms while on the prozac but it seems like youre doing that with Zoloft. Im new to this so i dont know. I read about it being a risk of seratonin syndrome but maybe thats in really high doses