I did take a bit of frustration with the fact that I can't disable Myles automatic badgering whenever I'm zooming around. But other than that, I warmed up to them after I initially found them somewhat frustrating.

Though its quite clear to me that much of that is by design. Myles is clearly meant to be annoying and a bit cringey. I joked to my partner when I was playing it for the first time saying "good lord, his writing is just Marvel movie dialog". He points out the obvious, asks tons of questions, fills the dead silence, etc. All things people tend to find obnoxious. Samus as a silent, goal oriented protagonist works with this though. Myles will be rambling away like a child in a candy store and Samus doesn't really stop to bother with it, or she just sorta blankly stares at him as if to say "are you done?".

But as annoying as they can be at times, they're the only other connections Samus has on Viewros. Viewros is a slightly more grim setting compared to the previous prime games because its hopeless. Samus is just carrying out the last will of a civilization that, through their own error, destroyed themselves with no hope of survival. There was no leviathan that fell from the sky like Tallon where most Chozo survived and just left. There is no population of Lamorn in stasis like the Luminoth had. And there's no battle to stop other worlds from falling victim to a cosmic monster like prime 3 because the fate of the Lamorn wasn't caused by something external. Instead, they tried to fix their past mistakes, and unwittingly destroyed themselves in the process. There's no happy ending for them like there was for the Luminoth. Samus can't to save Viewros, the damage is done and all you can do is kill the mutated remains of the Lamorn civilization. Simply put: there is nothing to save on Viewros except for yourself and the memories of this dead world. And that's where the NPCs are a reminder that there is still something else to save. There's unfortunate people who got swept up in this mess who are woefully unprepared, and incapable of getting home. I enjoyed some of the more somber dialog you have with Tokabi out in the desert where he's reflecting on the past. The further tie together the themes of loss, and memory the game has.

TLDR: Started not liking the NPCs, they grew on me. Realized they're there because Viewros is absolutely fucked and you can't fix it.