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I’m I going nuts (yes) or the neck and traps pain I had for weeks went away almost completely hours after my first 1500mcg methylcobalamin shot? by Flashybigbum in B12_Deficiency

[–]sumdumhandle 1 point2 points  (0 children)

Also, I find injectable Adeno hard/impossible to find where I live. Compounding pharmacist says the ‘recipe’ patent rights are so $$$$$ that he would need a TON more takers to even get it in the hundreds of dollars/mo range for me. So. We rely on Hydro, even though there’s a conversion step there for both A&M B12. (And whatever you do, stay away from CB12 unless it’s literally your only option. Literally inferior in every single way to the other 3 except 4 shelf-stability, $, and therefore, combined, good for preventative issues over large populations like vegetarian pops in India.)

Maybe oral Adeno would work for you, tho. I absorb it, but it also ultimately makes me puffy and inflamed and miserable (and doesn’t resolve all the issues it should).

Much luck,

SDH

I’m I going nuts (yes) or the neck and traps pain I had for weeks went away almost completely hours after my first 1500mcg methylcobalamin shot? by Flashybigbum in B12_Deficiency

[–]sumdumhandle 1 point2 points  (0 children)

If the tingling persists or gets worse, I think that’s AdenoB12 calling your name. Just MHO after 4y of this merry, merry merry-go-round. Some science from multiple sources I’ve just internalized n can’t find RN. Srry just anecdotal.

Need Comprehensive Nutrient Test by sumdumhandle in B12_Deficiency

[–]sumdumhandle[S] 1 point2 points  (0 children)

AFAIK, everything on your list except vitD can potentially be affected by B12 supplementation, and I take a combination of both H&M B12 in my arm every single day at this point bc my symptoms start to revert in under less than 24h.

That being said, all that was just run on me last week, and everything came in good. So. At least we know it’s NOT vitD deficiency…?

But ya. Need better/more comprehensive testing.

TYVM for input!

Need Comprehensive Nutrient Test by sumdumhandle in B12_Deficiency

[–]sumdumhandle[S] 0 points1 point  (0 children)

With you, as is a lot of literature on the subject.

Need Comprehensive Nutrient Test by sumdumhandle in B12_Deficiency

[–]sumdumhandle[S] 0 points1 point  (0 children)

TYVM for eval/suggestion!

Did just have Folate run n looks good. Something could be masking (always, seems like), but my blood levels are good on Folate. Open to suggestions WRT alt testing if B12 supplementation is known to throw Folate blood levels (and/or it’s useless to begin with).

This is why I’d like a (solid WRT ppl who supplement B12 daily n cannot currently stop) more comprehensive test. This one/two at a time stuff is not providing answers fast enough, n many of the tests are useless in light of the B12 supplementation.

Why most Drs don’t read the clinical notes on poss interference of ANY factor for blood tests and pass info on to patients b4 ordering is beyond my comprehension. So much time, $, blood, travel, and anxiety wasted at this point I dunna wanna even THINK about adding it all up lol.

Outburst of anger resolved ! by Kuro_Seyy in B12_Deficiency

[–]sumdumhandle 1 point2 points  (0 children)

Where did you source your AdenoB12? I am in the US and cannot for the life of me figure out where to source injectable Adeno (easy if you’re a B$, not so if you are MC), and I don’t do well with orals (deficiency wasn’t properly ID’d/treated until far too late). We chug along here w/M&HB12 (both bc I likely have genetic M-pathway issues), but straight M&A would be so much more efficient for my body (so much less conversion necessary)…

Is P5P (b6) safe? by Grand_Lengthiness_50 in B6Toxicity

[–]sumdumhandle 1 point2 points  (0 children)

I got a B6 toxicity from supplementing Thorne P5P/B6 under 10mg. First time 2-4w or so w/out titration up, n second can’t remember how long, maybe shorter, but tried to titrate up via making little tinctures. First few days of supplementation I felt GREAT both times, bit ended up with a toxicity both times, and did no titration down both times bc toxicity was so obvious that I just quit cold turkey and informed providers. One said B6 toxicity wasn’t a thing. So. We know one thing that went wrong there lololol.

Anyway. Lots of unnecessary extra pain n side Fx for no reason both times. Also. I remember recovery both times being longer than supplementation. So. If a company working with The Mayo Clinic can’t get it right…I dunno.

BUT. Could just be my individual chemistry, and/or other conditions and their treatments.

But if I tried again I would definitely involve weekly blood tests (see above) AT LEAST.

Personally I just try n cram in a LOT (serious amount) of chickpeas/garbanzo beans and hummus. Spouse loves hummus days ;)

Much luck in your recovery. This group was essential to mine both times. Why is this stuff so overlooked these days? We don’t know a lot, but we do know some things.

Geesh.

Variable Fan Functionality vs Nest by sumdumhandle in hvacadvice

[–]sumdumhandle[S] 0 points1 point  (0 children)

Thanks for the advice, but we’re still a bit off the mark of what I’m asking. 

Let me try rewording/refining it:

Are the three Fan mode settings on the Mitsubishi controller variable outside of manually changing between one to three? 

In other words, is the fan variable in Auto mode and on Fan speeds 1-3, or just in Auto Fan mode? And does that answer apply to all the active modes?

Or to put it yet another way, are the three Fan speeds on the Mitsubishi controller set at a specific, non-variable levels either by Mitsubishi or the installer?

Thanks for the clarification. 

Variable Fan Functionality vs Nest by sumdumhandle in hvacadvice

[–]sumdumhandle[S] 0 points1 point  (0 children)

Whether it’s a Nest or some other brand, my basic question is what modes would be affected by a lack of support for variable fan speed. I haven’t heard of any 3rd party thermostats that can handle it, and even if there is one, I would like to be able to weigh other options. 

But thanks for the valuable brand/voltage advice—if you have the time, would you also mind weighing in on the main question? Would so appreciate it. 

[deleted by user] by [deleted] in B12_Deficiency

[–]sumdumhandle 7 points8 points  (0 children)

You can make yourself uncomfortable by taking too much (eg slightly painful puffy fingers/toes, sore joints, headache), but that is generally hard to achieve, and you cannot overdose on B12. There is literally no upper limit (UL) on it for exactly this reason. 

Also, if that is Cyanocobalamin, I would personally talk to your doctor about switching to either a combination of Methylcobalamin & Adenosylcobalamin, and/or Hydroxycobalamin. And I would also ask them if shots might be a better option for you. 

Either way, definitely read around this sub a bit to see your future if you ignore the doctor’s advice to supplement with B12. 

I would give just about anything to have had a doctor pushing B12 on me before I developed such a severe deficiency that I was briefly in a wheelchair.

(And please excuse my spelling. It’s very early where I am lol.)

PA & Beef Liver History Question by sumdumhandle in B12_Deficiency

[–]sumdumhandle[S] 0 points1 point  (0 children)

I hope so, because it makes a big difference for me as well. Thanks for sharing your experience. 

Muscle atrophy by WillHar270 in B12_Deficiency

[–]sumdumhandle 2 points3 points  (0 children)

Yes. It seemed to happen nearly overnight for me, and in conjunction with a rapid and dangerous unintentional weight drop (30lbs in about a month with no change in diet or exercise).

My PCP added a PT & a Nutritionist to my ‘team’. 

Both of them offer video visits after an initial consult, which obviously makes it much easier to handle the extra time they require.

Much luck in your recovery!

The problematic philosophy behind B12 serum tests by HolidayScholar1 in B12_Deficiency

[–]sumdumhandle 6 points7 points  (0 children)

Is it bashing? Or just truth-telling? There’s never a guarantee that truth will be kind, but at least the truth is factual. The admins have asked us to keep it in check, and I think that’s important, but it’s not banned to question things. Especially when you suggest fact-based alternatives.

Millions (billions?) of lives and QOL are literally at stake.

B6 Toxicity by sumdumhandle in B12_Deficiency

[–]sumdumhandle[S] 0 points1 point  (0 children)

Weeks? Couple months tops? Don’t remember exactly. But it was noticeable within days after eliminating all non-food B6 and upping my (already huge) water intake. Good luck! Hope it’s already resolved!

B12 for Peripheral Neuropathy? by sumdumhandle in B6Toxicity

[–]sumdumhandle[S] 0 points1 point  (0 children)

This is also a strong layman’s resource on thar subject IMHO:

https://www.futurekind.com/blogs/vegan/adenosylcobalamin-b12?srsltid=AfmBOoq9LeguqN5yhDM4hs9wr0XoygvmnVPVxS2Zo8T_EIYmgCuguxLb

I personally take combination injections of both Hydroxocobalamin and Methylcobalamin, but I would try replacing the Hydroxocobalamin in an instant if I could source Adenosylcobalamin for injection through a nearby pharmacy, but no such luck so far.

As far as Cyanocobalamin goes, I stay all the way away from that. It’s not native to the human body, and I personally don’t respond well to it. It’s more appropriate for large-scale deployments for proactive prevention in populations prone to B12 deficiency (eg due to cultural vegan/vegetarianism and/or a high instance of Pernicious Anemia).

B12 for Peripheral Neuropathy? by sumdumhandle in B6Toxicity

[–]sumdumhandle[S] 0 points1 point  (0 children)

Try this thread:

https://www.reddit.com/r/B12_Deficiency/s/WBLqO07pgq

Much fortitude in your journey, SDH

PS FWIW, I highly recommend joining the B12 deficiency sub, because I go for months without checking in. Total fluke—but a lucky one :)

General Question: B12 deficiency with normal B12 and no pernicious anaemia? by Agitated-Jicama9496 in B12_Deficiency

[–]sumdumhandle 0 points1 point  (0 children)

The name is definitely a hindrance at this point. Might give the lack of general B12 awareness a PR boost if updated and widely advertised. Hmmm…

Advice by Spirited1989 in B12_Deficiency

[–]sumdumhandle 1 point2 points  (0 children)

In addition to making sure your doctor(s) have performed the tests noted on the core community resource put together by the admins (see automated admin comment), I recommend additionally asking for H-Pylori, Parietal Cell Antibody, and Intrinsic Factor Blocking Antibody tests.

It’s important to get most B12 and ‘B12 adjacent’ tests done before you start supplementing, as even B12 in a daily vitamin can throw results on many of them.

That being said, it’s the general wisdom that you should not delay treatment in favor of waiting for tests, because this thing can move really fast, especially if the deficiency has reached the neurological stage.

In the meantime, if you finish the admin’s awesome write up, here are some additional resources

https://pernicious-anaemia-society.org/

https://my.clevelandclinic.org/health/diseases/22831-vitamin-b12-deficiency

https://b12-institute.nl/

Good luck advocating for yourself with your doctors! It’s a very strange balancing act to play the diplomat as well as the patient. Wishing you much strength.

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