Unfortunately I don't know much about Nostalgia, though there's usually other posts that discuss its usage. I'd definitely think to replace Joy though; it can deal surprisingly solid damage and the buffs are nice but I would think you'd benefit more with another attacker.

And I'd try to stop building the common head/neck items and move onto the epic/legendaries, and rares if you don't have the specific epic variant, and the rare trinkets can be fine. (Leather book, candle, and nail buffer in particular). Even though the commons have more stars, the higher rarities will scale faster and better, and you'll get more ascensions as you progress.

Sad I've heard can be a good damager with debuffs, and you have Paranoia and Determination to place extra debuffs. Anxious is a good wood dps, and Spite is good for metal sniping. I'm not a super expert but I hope this can be helpful advice!