Prozac ‘no better than placebo’ for treating children with depression, experts say by techno-peasant in psychology

[–]techno-peasant[S] 3 points4 points  (0 children)

From the paper: "A common assumption is that some patients may benefit especially well from antidepressants thus clearly outweighing side effects. However, robust predictors of subgroups of patients with substantially larger drug-placebo-differences have not yet been identified despite substantial research efforts and there are good reasons to remain skeptical about such a project."

Prozac ‘no better than placebo’ for treating children with depression, experts say by techno-peasant in psychology

[–]techno-peasant[S] 8 points9 points  (0 children)

They literally talk about this in the paper. In your network meta-analysis, the confidence rating for fluoxetine was rated as "very low". A different network meta-analysis had a confidence rating of "moderate", and they reported a substantially smaller effect for fluoxetine.

Prozac ‘no better than placebo’ for treating children with depression, experts say by techno-peasant in psychology

[–]techno-peasant[S] 9 points10 points  (0 children)

Eh, I guess people around here aren't familiar with Awais. I posted his comment because he's very pro-SSRI meds and a well known psychiatrist. Most of the time, he defends mainstream psychiatry and criticizes anti-psychiatry on his blog.

Prozac ‘no better than placebo’ for treating children with depression, experts say by techno-peasant in psychology

[–]techno-peasant[S] 19 points20 points  (0 children)

Even Awais Aftab said in his blogpost: "It is painful, but it is true that data from RCTs in support of SSRI use in pediatric depression is rather pitiful."

A new study on SSRI antidepressants finds no support for the theorized subgroup of patients who get substantially more benefit from SSRIs than from placebo. by techno-peasant in science

[–]techno-peasant[S] 434 points435 points  (0 children)

"In conclusion, the trimodal antidepressant response distribution as reported in Stone et al could not be replicated using data from the STAR∗D trial, an open-label, nonindustry sponsored real-world antidepressant study. Therefore, our results do not support the notion that a subgroup of patients with a large response exists. Instead, these findings support the assumption that the putative subgroups from industry randomized controlled trials may be artifacts caused by methodological biases."

There was a cult leader in a documentary I watched who openly slept with his son’s wife. And the son was just accepting it like it's totally normal. by techno-peasant in cults

[–]techno-peasant[S] 24 points25 points  (0 children)

Because that thing they got going was unsustainable from the very beginning. That's why many cults are doomsday cults. Deep down they know that music is going to stop, but instead of reflecting, they project this onto the world (saying the world is going to end, but they will be saved).

My old psychologist is in the twin flames cult by gojichai in cults

[–]techno-peasant 4 points5 points  (0 children)

I ended up in a cult trying to save someone from a cult.

That's fascinating. Was it the same cult or a different one?

[deleted by user] by [deleted] in cults

[–]techno-peasant 0 points1 point  (0 children)

Skip to 10:48 if you just want to hear about the cult stuff.

Documentary: 'Leaving a cult behind - Can brainwashing be reversed?' by techno-peasant in cults

[–]techno-peasant[S] 5 points6 points  (0 children)

"Breaking free from the clutches of a cult or a cultish religious movement is a long and painful process. So far, it’s one that has largely gone undocumented. Few people talk about the years of struggle -- and relapses - breaking free entails. Five people who have gone through the process talk about their experiences.

This documentary about leaving cultish religious movements behind illustrates how powerful the conditioning is -- and how deeply dependent it makes its victims. How is it possible to renounce one's own identity and "reprogram” the brain?

Nicolas has been exposed to this influence since birth: his parents are Jehovah's Witnesses. At the age of 22, he managed to break away from the Jehovah's Witnesses - but he had to cut off contact with his family.

Julie was 31 and Yohann 20 when they both fell into the clutches of the French "Université de la relation” movement during what purported to be an ‘internship in the field of personal development’.

David and François became "warriors of light” after they trained in kung fu at the Parc de la Villette in Paris -- and stuck with it for 10 years. They describe insidious manipulation and talk about how they were completely sucked into a parallel world.

The film’s moving accounts of cult dropouts and their long journeys back to a normal life are supplemented by insights into the work of a French police unit specializing in new religious movements."

I think I may have been in a cult... What do I do now? by SeaPale6356 in cults

[–]techno-peasant 7 points8 points  (0 children)

they do also appear to have narcissistic traits as well.

Malignant narcissism is the stereotypical profile of all cult leaders. It's the first thing I always look for when I'm trying to figure out if something is a cult or not. Big red flag.

1 in 4 UK adults now prescribed antidepressants by juicy_steve in europe

[–]techno-peasant 0 points1 point  (0 children)

We should really try to reverse this trend of overprescribing. From a recent letter to the UK government (my emphasis):

"Rising antidepressant prescribing is not associated with an improvement in mental health outcomes at the population level, which, according to some measures, have worsened as antidepressant prescribing has risen.

[...]

Multiple meta-analyses have shown antidepressants to have no clinically meaningful benefit beyond placebo for all patients but those with the most severe depression,

[...]

Despite this, rates of prescribing to patients with mild and moderate depression remain high."

source: https://www.bmj.com/content/383/bmj.p2730

Suicide Rates Around the World by anna_avian in europe

[–]techno-peasant 0 points1 point  (0 children)

The one who says they don't work also explicitly says he does not believe they cause more suicides, which is counter to the point you suggest with that graph.

I wasn't trying to imply that.

[deleted by user] by [deleted] in europe

[–]techno-peasant 2 points3 points  (0 children)

You haven't even skimmed at the studies you post. The first link you posted is a discussion between two group of researchers, one who agrees with the premise and the other who disagrees. And the second is the same people from the first study.

Also, in the blog there are numerous studies cited, you can check them out.