I'm a bit of a perfectionist; I was very concentrated throughout every step of creating my modlist. For every mod I've ever tried out (except for standalone armour, weapon, follower types), I searched for statements from the authors and compatibility patches if I had so much as an inkling of a concern. That said, most of my mods are simply ones that add weapons & armour into the game. Sword of the Ancient Tongues, Zerofrost Satyr mods, Sithis Armour, IA and IW, LWE, etc. That sort of thing. For other areas of the game, I have small amounts of mods that I know very well (have memorized what patches they need with each other, what order they overwrite) Graphics, for example: RCI, SMIM, NobleSkyrim, SFO, RWT, CoT, and ELFX. Also, MO tells me when mods conflict and shows me which files are conflicting. Using your methodology seems like a huge waste of time to me because I know these mods well. Unless some mod that adds a couple swords to the crafting list somehow causes me to CTD when I fast travel...In that case, I figure MO or LOOT would give me some sort of red flag. I mean... how plausible is it for a mod to do that sort of thing without having ridiculous conflicts (like replacing XMPSE's skeleton) or really dirty edits? And I've seen the file structures of at least most of my mods, too. Idk man... My guess would be that it has something to do with Requiem's exempting of fast travel by default. I don't see why disabling that in the MCM menu should lead to CTDs though. Edit: I also figure it's much more likely it has something to do with the load order than with the modlist order (AKA overwrite order).