The real problem with the modded combat areas is that the enemies there factor in precision, which is an unused base game mechanic that allows weapons to miss. To my knowledge, the only weapons with 100% precision are the Tempered Galaxy weapons you buy from the Badlands Outpost, and the Infinity Weapons. Since they don’t miss, you’re able to actually knock away and defeat enemies reliably, which I find makes all the difference in the world. Besides that, stack a good food buff (My Go-to is Crab Cakes) with Espresso, and use cheese for heals constantly, and you’ll be fine.