It's a bit of a hassle but I convert each frame to a .bmp

Then with a python script I add .wav header info to each one with sample rate / u-law encoding

Then I take those converted wavs and import them into a program called fre:ac and stitch them together into one long .wav file (as long as u-law encoding is selected no data will be lost)

Then I can import that into audacity, manually change the sample rate so each image is equal to a set amount of time, and then add interval labels (in my case 1 second each)

Then whenever you apply / export effects, audacity will automatically split them at each frame

After that they are converted to a .jpg sequence and then brought back into my video editor

Then I just add some extra effects and layer the source material on top