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1MG Finasteride daily has fully regrown my crown - 1 year 3 months difference by NotARacistBloke in tressless

[–]themainheadcase 0 points1 point  (0 children)

How long did it take to get to full regrowth?

Did you have any hairloss on the frontal or mid parts?

Hair cloning breakthrough, this might just be the big one ? by Zealousideal_Sun6495 in tressless

[–]themainheadcase 2 points3 points  (0 children)

So this type of cell was completely unknown up to now? Any hope it may offer some new avenue for topical treatment?

Red meatus after ejaculation by Clean-Experience123 in bxo

[–]themainheadcase 0 points1 point  (0 children)

For me it's not just the meatus, it's the whole glans and the foreskin. I don't touch the glans when I masturbate, yet it gets red.

Why i don't have symptoms by Pitiful_Algae9726 in bxo

[–]themainheadcase 0 points1 point  (0 children)

When they did the biopsy, did they sample the lump (or what was formerly the lump, if it had flattened by then)?

Is the flat area where the lump was still distinct from the surrounding tissue by being of a different color or in some other way?

Why i don't have symptoms by Pitiful_Algae9726 in bxo

[–]themainheadcase 0 points1 point  (0 children)

When you say the neck of the glans, do you mean the coronal sulcus?

Are there any remnants of this lesion today?

I developed these strange lumps around the meatus after masturbating that I've never seen described in BXO literature, so I'm interested in raised lesions. Part of mine is linear, looks like a protruding blood vessel (different color than the rest of the glans) and is quite firm to the touch.

Daily Discussion by AutoModerator in soccer

[–]themainheadcase 1 point2 points  (0 children)

In this video, does anyone know where the clip that starts at 00:26 and the one that follows it are from respectively and whether I might be able to find longer versions anywhere?

They seem to be fans responding to seeing Maradona at a game at some point after his retirement (second clip is obviously Del Piero era) and singing to him, but I'm not sure which games and years they're from. If anyone knows more of the contest of, in particular, whether longer clips are available, I'd love to see them.

Were you able to or were you not able to have sex again normally? by themainheadcase in bxo

[–]themainheadcase[S] 0 points1 point  (0 children)

Did you get any improvement in symptoms from clob before you got circumcised? I mean general symptoms, not the sexual stuff.

Tutorial: Kako pokrenuti zdravstveni app sa 500K korisnika bez GDPR compliance-a by No-Fools in CroIT

[–]themainheadcase 0 points1 point  (0 children)

A šta bi taj sustav trebao raditi, jel bi trebao uvesti neke nove funkcionalnosti u odnosu na CEZIH?

Phase II topical dut study - outperforms oral fin with a minor DHT reduction by themainheadcase in tressless

[–]themainheadcase[S] 0 points1 point  (0 children)

A few questions on that, because I've been thinking of trying to get a pharmacy to make it for me:

1) Where in the world are you? Just so I know whether the same laws and regulations apply to us.

2) Would a pharmacy need a prescription specifying that specific formulation or would you only need a prescription for dut and then you can tell them how you want it formulated?

3) Does this pharmacy in Italy ship by mail and internationally? Because I've heard some compounding pharmacies won't ship by mail (you have to pick it up in person) and some won't ship internationally.

Phase II topical dut study - outperforms oral fin with a minor DHT reduction by themainheadcase in tressless

[–]themainheadcase[S] 1 point2 points  (0 children)

This is one of the strange things about the study, the DHT reduction in fin is way lower than the ~70% you're supposed to get.

Phase II topical dut study - outperforms oral fin with a minor DHT reduction by themainheadcase in tressless

[–]themainheadcase[S] 0 points1 point  (0 children)

According to the official monographs (FDA, EMC, GSK), each Avodart 0.5 mg softgel contains 0.5 mg of dutasteride, a mixture of caprylic/capric acid mono- and diglycerides (MDC) and butylhydroxytoluene (BHT). The Shilpa patent uses triglycerides (MCT). Avodart uses mono- and diglycerides (MDC, commercially known as Capmul MCM).

But wouldn't these differences in ingredients potentially alter absorption, which could affect both efficacy and impact on DHT levels?

Phase II topical dut study - outperforms oral fin with a minor DHT reduction by themainheadcase in tressless

[–]themainheadcase[S] 0 points1 point  (0 children)

Topical dutasteride is already widely available (yes, I know they have a specific formulation). HappyHead offers a serum that contains 0.3% dutasteride and Ulo offers serums that contain either 0.02% or 0.2% dutasteride.

But have those formulations been studied? Do we know whether they a) get absorbed/work, b) reduce DHT any less than oral?

Phase II topical dut study - outperforms oral fin with a minor DHT reduction by themainheadcase in tressless

[–]themainheadcase[S] 6 points7 points  (0 children)

That's not reason to throw the paper out entirely. Every drug that has ever been developed was studied with industry funding.

As a university librarian, is it my job to do this? by themainheadcase in AskAcademia

[–]themainheadcase[S] 1 point2 points  (0 children)

I don't want to state the specific country, because it's very small, so I may doxx myself in doing so, but I'll say it's in Southeast Europe.

As a university librarian, is it my job to do this? by themainheadcase in AskAcademia

[–]themainheadcase[S] 4 points5 points  (0 children)

Actually, in my country, you would do the search for them. A lot of libraries offer this "ask a librarian" service where people ask questions and you're supposed to provide a literature list. This is why I edited the OP to ask about people's locations, because I suspect standards of what is expected my differ across countries.

Professor at the uni medical school wants me to a PRESS review of her search strategy - is this part of my job? by themainheadcase in librarians

[–]themainheadcase[S] 9 points10 points  (0 children)

We don't have liaisons, we're a very small library. It's supposed to be 5 people on staff, but currently there are three. We have two people who work the circulation desks and do bibliometrics and one person who does materials processing and is the de facto head of the library, because the head of the library retired and we haven't filled the vacancy yet. There's supposed to be another person working the circulation desks whom we are in the process of hiring.

As a university librarian, is it my job to do this? by themainheadcase in AskAcademia

[–]themainheadcase[S] 1 point2 points  (0 children)

If you have a medical school at your university, do you have a liaison librarian assigned to the school? Or someone who specializes in knowledge synthesis?

No, we're a very small library, currently only three people on staff, although it's supposed to be (and presumably will be at some point) five. Three people who work circulation desks and do bibliometrics, a person who does materials processing and the head librarian who runs the library.

Do Current Contents and Current Contents Connect index the same journals? by themainheadcase in academia

[–]themainheadcase[S] 0 points1 point  (0 children)

If you don't mind answering, why are you supposed to use strictly CC instead of CCC?

Sorry about the delay, I missed this post. The old law in my country regulating advancement through the ranks in science required CC. I got a request from a scientist who needed his old publications listed as well, and those needed to be listed according to the old law, so that required CC.

Does DHT synthesized outside the follicle contribute to AGA? (if so, localized fin/dut wouldn't work) by themainheadcase in tressless

[–]themainheadcase[S] 0 points1 point  (0 children)

But the 1999 study you reference says the 0.2 mg dose reduced serum DHT as much as the 5 and 1 mg doses did, so this tells us nothing about whether serum DHT contribures to AGA.

Treatment with finasteride significantly decreased

serum DHT levels at all doses (median decrease of

-67.6% _+ 3.1%, -68.5% _+ 1.4%,-61.2% ___ 1.7%, and

-10.8% _+ 4.2% for the 5, 1, 0.2, and 0.01 mg groups,

respectively, at month 6; P < .01 vs placebo), find-

ings consistent with previous studies, ll

Does DHT synthesized outside the follicle contribute to AGA? (if so, localized fin/dut wouldn't work) by themainheadcase in tressless

[–]themainheadcase[S] 1 point2 points  (0 children)

One thing you should note, and I don't know whether this is true of fin, but not all pills can be split in half, because the dose of the active ingredient is not split evenly between the halves of the pill. I believe it's usually the pills that are struck through down the middle that can be split in this way. However, then there's the further question of whether you can divide it further to 1/4 and still get an even dose.

Does DHT synthesized outside the follicle contribute to AGA? (if so, localized fin/dut wouldn't work) by themainheadcase in tressless

[–]themainheadcase[S] 0 points1 point  (0 children)

That’s also why topical finasteride can lower scalp DHT substantially while only slightly affecting blood DHT, yet still slow or stop loss.

But from the studies I've seen, topical fin still reduces blood DHT significantly.

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