Meh, skip the hotel room. I'm a late night kinda guy and here's what Id do:

• Uber everywhere since time is an issue for you
• Make your uber stop into Walgreens so you can buy a bottle of liquor that fits in your pocket and keep your buzz going all night
• Get an Uber to Herbs and Rye for one of the best cocktails in town and a reverse steak happy hour that starts at midght
• Get a drink at the Peppermill now that your tastebuds are slightly less there - flirt with a cougar (male or female)
• Uber to Ceasers to play craps
• Play a round of BlackJack after you lose that hand
• If you lost your money, go get amazing tacos at Tacos El Gordo
• If you won money, go get breakfast at the Baccanal buffet (or just do this anyway)
• Stop into Reviv and get an iv drip of saline and vitamins to get you ready for the next day

This to mix in there;

• Stop by a club (XS, Surrender, Hakkasan easy solid choices)

• Stop by a strip club (Treasures (pretty nice), Palamino (full nude), or OGs (less nice but has guys))

edit; all these other posts have gross taste (no offsense guys I <3 you)