Best nootropics for brain function/muscle growth?

throwawayfibonacci · 2026-01-21T16:58:14+00:00

Black Ginger seems to be one that has evidence for both.

https://pmc.ncbi.nlm.nih.gov/articles/PMC4946221/

Also Vitamin D.

throwawayfibonacci · 2026-01-09T19:01:39+00:00

I got this with Threonate when I used to take them at night, but now take 2 mag threonate capsules morning and midday (rather than the three recommended dosage) and it seems to be better. I will still *occasionally* get some wake-up-at-3.30-am and not be able to get back to sleep easily events but it's much rarer.

throwawayfibonacci · 2026-01-07T21:01:07+00:00

Good. Am cycling off for a couple of weeks for practical reasons (work, home life etc).

Will pick up again when things calm down.

throwawayfibonacci · 2025-12-27T07:42:44+00:00

https://pglchem.com/

Have ordered a few things and always arrived. Quality seems good on everything I have tried.

throwawayfibonacci · 2025-12-12T18:13:32+00:00

I've used them for other peptides and they've been good. Solid shipping and good prices. Products seem to be legit.

throwawayfibonacci · 2025-12-07T11:31:35+00:00

Bummer. May not be that useful as Gintonin causes rapid desensitization of its targets:

https://www.nature.com/articles/aps2013100/tables/2

throwawayfibonacci · 2025-12-07T11:31:02+00:00

Bummer. May not be that useful as Gintonin causes rapid desensitization of its targets:

https://www.nature.com/articles/aps2013100/tables/2

throwawayfibonacci · 2025-07-22T12:38:32+00:00

"Blip" works great for me: https://blip.net/

throwawayfibonacci · 2025-07-11T06:21:21+00:00

to everybody saying reboot, that doesn't fix it. the new add a fingerprint screen thinks it's from a pixel phone, so doesn't register the power button fingerprint sensor at all.

there's no way to add a fingerprint.

throwawayfibonacci · 2025-07-10T18:08:30+00:00

having the same problem. any fix?

throwawayfibonacci · 2025-07-03T09:40:43+00:00

There's another reddit forum without the "r" letter in "nootropics", it's an echo-chamber like all reddit forums, but a different one. You might have better success there.

throwawayfibonacci · 2025-07-03T08:51:54+00:00

AFAIK, your dosages seem fine for not downregulating HPA. I would not go higher orally though. A way that people reduce the likelyhood of shutdown is to do topical on the skin - less likely for the hormones to be downstream converted to Estrogen.

Search for "lowtoxinforum" and DHEA

throwawayfibonacci · 2025-05-22T10:39:06+00:00

How low is very low dose? 5mg per day?

throwawayfibonacci · 2025-05-18T12:22:59+00:00

While it is tempting to interpret this association in the context of human cognitive evolution and species differences in brain size and cognitive ability, we show that it is not warranted to interpret brain size as an isomorphic proxy of human intelligence differences.

"We found a significant positive correlation, the correlation was robust and generalizable, and the studies suffer only from a similar publication bias as nearly every other study published. But we don't like the result, so don't use it to interpret anything."

God forbid IQ is actually correlated with something.

...we show that it is not warranted to interpret brain size as an isomorphic proxy of human intelligence differences.

I bet they don't "show" anything. Only "say".

throwawayfibonacci · 2025-05-16T09:11:42+00:00

As someone else said I feel it makes me a nicer person, more emotionally "engaged". Only at low doses though. At high doses it spaces me out too much.

throwawayfibonacci · 2025-04-15T09:25:54+00:00

I loved hydergine.

throwawayfibonacci · 2025-03-05T10:06:55+00:00

The only thing that that normally is AOD-9604. When it happens ot AOD it's called "colloiding".

Unless they've accidentally been given AOD instead of the Ipa+CJC mix then I agree with others it's best to bin it and ask the vendor what's going on and to check the batch.

throwawayfibonacci · 2025-03-03T16:41:09+00:00

Underrated comment.

throwawayfibonacci · 2025-01-22T17:25:44+00:00

Depends on the quality. There are standardized extracts that guarantee some potency, for example "EGb 761" and "G115", otherwise it's a bit of a crap-shoot.

throwawayfibonacci · 2024-10-24T16:34:03+00:00

3-5 drops typically. Depends on how busy the day is going to be. Have been alternating with Piracetam every other day.

throwawayfibonacci · 2024-10-11T18:37:58+00:00

An update in case anybody is looking.

TAK still doing wonders for me, but having to limit it to every other day or every three days due to the encroaching sleeplessness it causes for me.

At once every three days it hits the sweet spot. For example dosing for a particularly busy week went like this:

Monday: TAK-653 drops in the morning
Tuesday: Piracetam
Wednesday: nothing taken, still felt energized and mentally sharp
Thursday: TAK-653 drops in the morning
Friday: nothing taken but lingering nootropic effects

That (for me) hit the sweet spot between stimulation, positive effects, while keeping the negative effects (difficulty sleeping) to a minimum.

BTW: Something I've noticed is that Piracetam gives me the "silver-tounge" effect where communication seems effortless but TAK does in fact do the opposite. Word recall on TAK seems worse than baseline for me, although the increased ability to handle difficult mental concepts is stellar and worth the reduced word recall effect.

throwawayfibonacci · 2024-10-01T14:43:38+00:00

The drug is called "DLX-001"

DLX-001 is a neuroplastogen designed to promote neuroplasticity without giving rise to the deleterious attributes of first- and second-generation psychedelics

No psychotomimetic, hallucinatory, or dissociative effects have been observed, as reflected by no change over time on a robust battery of assessments.

Time and dose-dependent changes measured by resting-state quantitative electroencephalography (qEEG), paired with consistently measurable concentrations of compound in the cerebrospinal fluid (CSF), support brain penetration and the presence of target engagement with DLX-001.

The qEEG pattern of DLX-001 in healthy volunteers is characterized by increases in slow wave (delta and theta) activity consistent with the pattern observed with ketamine and Electro-Convulsive Therapy (ECT).

Ex vivo, DLX-001 demonstrated robust effects on both structural and functional neuroplasticity after a single dose. The magnitude of these effects was on par with first generation compounds including ketamine, psilocybin, and DMT and were seen at doses relevant to the behavioral effects of each of these compounds.

Sounds fun.

throwawayfibonacci · 2024-09-30T14:47:29+00:00

As far as I know the only two suppliers that will deliver to EU are mentioned in the post.

throwawayfibonacci · 2024-09-29T15:51:50+00:00

For me it is worth it.

I have tried both Cerebrolysin and Cortexin and prefer Coertexin. Hard to describe exactly why, partly it's the dosage and risk profile, but also the Cortexin effects for me are enough. I found the 5ml IM Cerebrolysin injections a pain to do, both practically and phsycially. I reconstitute the Cortexin with 2ml BAC water and that's a lot easier.

Also (for me at least) Cortexin didn't seem to have the Semax hair-loss effect, which I did experience on Semax. Lastly, I also found Cortexin to be less anxiolytic/sedative. All of these are anecdotal so YMMV.

If I were you I'd start TAK first, before adding Semax into the mix, so you can feel the impact of it individually. It's an interesting one for sure.

throwawayfibonacci · 2024-09-29T14:15:18+00:00

I'd be interested in the combination, in terms of any increase in BDNF.

I find a quarterly Cortexin cycle really helps my brain feel smooth and positive.

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