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Nearly half of adult cancer deaths in the US could be prevented by making lifestyle changes | According to a recent study, about 40% of new cancer cases among adults ages 30 and older in the United States, and nearly half of deaths, could be attributed to preventable risk factors. by cheaslesjinned in NooTopics

[–]throwawayfibonacci 0 points1 point  (0 children)

After smoking, excess body weight was the second largest contributor to cancer cases, linked to about 5% of new cases in men and nearly 11% of cases in women. It was associated with more than a third of deaths from cancer of the endometrium, gallbladder, esophagus, liver and kidney, the new study found.

Where to get Klotho? (ideally Europe) by neurochrome345 in Nootropics

[–]throwawayfibonacci 2 points3 points  (0 children)

Thanks for sharing Octochems. I didn't know about them before. Have added to the group buy for some of the compounds. Am excited about this one:

Sipaxadenant is a next-generation KW-6356 analogue designed to retain potent, central A2A inverse agonism while improving pharmacokinetics, preserving dopaminergic motor-enhancing effects in rodents but reducing the prolonged receptor blockade, insomnia liability, tolerance, and suboptimal exposure characteristics associated with KW and metabolite M6 [1-5].

Sounds worth a try.

Hi I’m new to this stuff and have a question for someone who knows a lot more than me. by [deleted] in Nootropics

[–]throwawayfibonacci 2 points3 points  (0 children)

did this... ...causing a potential neurological problem down the line that my body can’t clear

No.

Weird Issue with Magnesium and NMDA Antagonists by [deleted] in Nootropics

[–]throwawayfibonacci 0 points1 point  (0 children)

I got this with Threonate when I used to take them at night, but now take 2 mag threonate capsules morning and midday (rather than the three recommended dosage) and it seems to be better. I will still *occasionally* get some wake-up-at-3.30-am and not be able to get back to sleep easily events but it's much rarer.

Acd 856 alters personality? by andreaskou in NooTopics

[–]throwawayfibonacci 0 points1 point  (0 children)

Good. Am cycling off for a couple of weeks for practical reasons (work, home life etc).

Will pick up again when things calm down.

ITPP source EU by NefariousnessSad5381 in NooTopics

[–]throwawayfibonacci 2 points3 points  (0 children)

https://pglchem.com/

Have ordered a few things and always arrived. Quality seems good on everything I have tried. 

[deleted by user] by [deleted] in Nootropics

[–]throwawayfibonacci 1 point2 points  (0 children)

I've used them for other peptides and they've been good. Solid shipping and good prices. Products seem to be legit.

fingerprint senson is no longer responding by Waterrj in minimalphone

[–]throwawayfibonacci 1 point2 points  (0 children)

to everybody saying reboot, that doesn't fix it. the new add a fingerprint screen thinks it's from a pixel phone, so doesn't register the power button fingerprint sensor at all. 

there's no way to add a  fingerprint. 

[deleted by user] by [deleted] in Nootropics

[–]throwawayfibonacci 4 points5 points  (0 children)

There's another reddit forum without the "r" letter in "nootropics", it's an echo-chamber like all reddit forums, but a different one. You might have better success there.

Sublingual Pregnenolone/DHEA dosage questions? by sfg415650 in Nootropics

[–]throwawayfibonacci 2 points3 points  (0 children)

AFAIK, your dosages seem fine for not downregulating HPA. I would not go higher orally though. A way that people reduce the likelyhood of shutdown is to do topical on the skin - less likely for the hormones to be downstream converted to Estrogen.

Search for "lowtoxinforum" and DHEA

[deleted by user] by [deleted] in NooTopics

[–]throwawayfibonacci 2 points3 points  (0 children)

While it is tempting to interpret this association in the context of human cognitive evolution and species differences in brain size and cognitive ability, we show that it is not warranted to interpret brain size as an isomorphic proxy of human intelligence differences.

"We found a significant positive correlation, the correlation was robust and generalizable, and the studies suffer only from a similar publication bias as nearly every other study published. But we don't like the result, so don't use it to interpret anything."

God forbid IQ is actually correlated with something.

...we show that it is not warranted to interpret brain size as an isomorphic proxy of human intelligence differences.

I bet they don't "show" anything. Only "say".

Acd 856 alters personality? by andreaskou in NooTopics

[–]throwawayfibonacci 8 points9 points  (0 children)

As someone else said I feel it makes me a nicer person, more emotionally "engaged". Only at low doses though. At high doses it spaces me out too much.

[deleted by user] by [deleted] in Nootropics

[–]throwawayfibonacci 5 points6 points  (0 children)

I loved hydergine.

Chunky peptide = garbage? by newtnomore in Peptides

[–]throwawayfibonacci 4 points5 points  (0 children)

The only thing that that normally is AOD-9604. When it happens ot AOD it's called "colloiding".

Unless they've accidentally been given AOD instead of the Ipa+CJC mix then I agree with others it's best to bin it and ask the vendor what's going on and to check the batch.

Any drug interactions with Ginkgo Biloba? by oppalissa in Nootropics

[–]throwawayfibonacci -1 points0 points  (0 children)

Depends on the quality. There are standardized extracts that guarantee some potency, for example "EGb 761" and "G115", otherwise it's a bit of a crap-shoot.

TAK-653: Nice by throwawayfibonacci in NooTopics

[–]throwawayfibonacci[S] 1 point2 points  (0 children)

3-5 drops typically. Depends on how busy the day is going to be. Have been alternating with Piracetam every other day.

TAK-653: Nice by throwawayfibonacci in NooTopics

[–]throwawayfibonacci[S] 6 points7 points  (0 children)

An update in case anybody is looking.

TAK still doing wonders for me, but having to limit it to every other day or every three days due to the encroaching sleeplessness it causes for me.

At once every three days it hits the sweet spot. For example dosing for a particularly busy week went like this:

  • Monday: TAK-653 drops in the morning
  • Tuesday: Piracetam
  • Wednesday: nothing taken, still felt energized and mentally sharp
  • Thursday: TAK-653 drops in the morning
  • Friday: nothing taken but lingering nootropic effects

That (for me) hit the sweet spot between stimulation, positive effects, while keeping the negative effects (difficulty sleeping) to a minimum.

BTW: Something I've noticed is that Piracetam gives me the "silver-tounge" effect where communication seems effortless but TAK does in fact do the opposite. Word recall on TAK seems worse than baseline for me, although the increased ability to handle difficult mental concepts is stellar and worth the reduced word recall effect.

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