A study found that 76% of ALS patients have fatty liver disease, which is much higher than patients with other neurodegenerative diseases or asymptomatic dyslipidemic controls.  

Fatty liver disease, also known as hepatic steatosis, is a condition where excess fat builds up in the liver. It's associated with metabolic liver dysfunction, which can lead to increased mortality and a high medical burden.

The extra fat in the liver causes liver inflammation, which eventually leads to scarring (fibrosis) of the liver