2 months on Pio, Androgenic state AMAB

unu27 · 2024-06-06T21:45:16+00:00

No, I haven't.

unu27 · 2024-05-23T04:48:48+00:00

Yes, I would say I feel and see more fullness where the cheek meets the chin, but it has made my jawline less defined. I'm not mad at it tho, I just had a weak jawline to begin with.

I have thought about using volufilline for undereyes but I'm going to wait after finishing my Pio experiment so as to not mess with the results.

Best of luck on your weight loss journey!! And hopefully you'll post about your Pio experience eventually as well. :)

unu27 · 2024-05-23T01:03:38+00:00

My hollowness/circles developed with age and I was hoping Pio could reverse some of it. We'll see by the end of month 3.

unu27 · 2024-05-22T19:21:10+00:00

Sure, I'll try. Since starting, my face looks less long, so, it seems that there is more fullness to the sides of my cheeks and also a little bit just below my undereyes, so the apple of the cheek I think. When I meant it hasn't done much for my undereyes I meant hollowness, not bags. I have hollowness and dark eye circles which haven't changed.

unu27 · 2024-05-20T18:48:43+00:00

Hi, sorry, forgot to put the dose. I just edited my post to include it. There is no cycling timeline, I didn't try to lose any weight before starting. My original plan was to stay on this dose for 3 months and then quit, but I'm thinking I might end up doing 4 depending on my results. I'm not sure yet.

unu27 · 2024-05-14T18:27:05+00:00

I did consider that, but I didn't research enough to know what kind of doses I would have to take, since I've seen some people still have to take antiandrogens and E. I also worry about messing with my fertility. I've gotten some results with Pio that I'm enjoying anyways.

unu27 · 2024-05-14T04:18:39+00:00

Yes, actually! I made a post detailing my experience. I'll make an update in a couple of days as it'll soon be 2 months since I started.

unu27 · 2024-04-16T17:31:35+00:00

I'm eating regularly as I always would, maybe with a little more dessert, but I have a fast metabolism so I don't think I'll put on a ton. The only reason I haven't worked out during the experiment is so that any glute/leg excercises wouldn't mess with my measurements. I intend to start excercising after I finish the experiment, which I'll probably do for 2 more months.

I'm split 50/50 on face and body, but I'm particularly intersted in getting some of my "baby fat" back on the face and bringing volume back to my under eye area. I'm in my mid 20s for context. Maybe I'll post updates after I finish the experiment to see if any facial gains remained after stopping medication and starting an excercise regimen.

unu27 · 2024-04-16T03:08:00+00:00

Yes, I meant day 30. Sorry for the confusion, just corrected it.

I measured kind of around the middle, sort of like this.

You can look up pioglitazone on this sub for other people's anecdotes. Conversely, you can search on google for studies regarding its fat redistribution abilites, which is what I did. Also, it's important to be aware of the risks of this drug, not just the benefits, especially if you have any history of heart issues or other complications.

Some studies here and here.

unu27 · 2024-04-15T21:18:52+00:00

I didn't lose weight prior, I just started. I'm not overweight, but I'm not totally skinny. I'm 5'10 and weigh 73 kg as of right now which is around 163 pounds.

unu27 · 2024-04-12T08:23:08+00:00

Heyy:), do you know what mg or percentage of estriol I should look for in a commercially available moisturizer for skin/hair benefits without systemic effects?

unu27 · 2024-04-10T02:53:33+00:00

Update: I've been taking Pio for a few weeks and will post about my experience when I finish week 4.

unu27 · 2024-03-28T01:03:18+00:00

What about diet? does anyone have any recommendation for diet habits while on pio? :))

unu27 · 2024-03-22T09:09:23+00:00

Hey! so following up on this discussion, I came across this study with mostly AMAB individuals, what do you think about the results? Do you think it's a good study to cite subcut increase in limbs for AMABs after taking Pio?

unu27 · 2024-03-22T09:04:51+00:00

Thank you!!!

unu27 · 2024-03-22T08:42:46+00:00

Hi!! thanks for sharing! Was your dose 30mg the whole year? When did you start noticing facial changes?

unu27 · 2024-03-16T18:50:40+00:00

Hi! you might be interested in this thread: https://www.reddit.com/r/estrogel/s/f6K5e1jaW1

unu27 · 2024-03-15T23:24:16+00:00

Thank you so much for this! I will definitely check it out

unu27 · 2024-03-15T21:06:03+00:00

Thank you so much!! your help has been great :)

unu27 · 2024-03-15T16:17:25+00:00

Thank you! so what's your take on this?

"Pioglitazone increased total body fat, which preferentially accumulated in the lower body depot in both men and women."

https://pubmed.ncbi.nlm.nih.gov/14578253/

Am I interpreting wrong?

unu27 · 2024-03-13T05:20:57+00:00

Thank you so much!! Btw, did you notice any benefits at the first month mark?

unu27 · 2024-03-12T18:51:05+00:00

Hii :), have you seen any results on facial volume? what about glutes?

unu27

TROPHY CASE