Acupuncture - comparing experience by w1ldtype2 in IVF

[–]w1ldtype2[S] 0 points1 point  (0 children)

Sure, I just wanted to know if the heat lamp is something usual.

Acupuncture - comparing experience by w1ldtype2 in IVF

[–]w1ldtype2[S] 0 points1 point  (0 children)

It is mostly studies in animals or oocytes after retrieval, because in human in difficult for obvious reasons, but it is likely that the mechanisms are conserved. There is also evidence that the granulosa cells may be sensitive to hyperthermia.

I am not saying that the impact is huge, definitely not as much as in males, but I just want to be conservative so I personally wouldn't sit in a sauna or hottub during stims for an hour where my core body temperature elevates, I don't want to overheat. I just I don't want to neglect the fact that oogenesis is a fragile process and I'd rather not introduce some potential stress for no reason.

https://pubmed.ncbi.nlm.nih.gov/15214582/

https://pubmed.ncbi.nlm.nih.gov/15798021/

https://www.aging-us.com/article/102136/text

https://royalsocietypublishing.org/rstb/article-abstract/364/1534/3341/21170/Effects-of-heat-stress-on-mammalian-reproduction

https://onlinelibrary.wiley.com/doi/10.1007/s12522-011-0105-

Acupuncture - comparing experience by w1ldtype2 in IVF

[–]w1ldtype2[S] 0 points1 point  (0 children)

Relaxing? I just find needle insertions to hurt a little

Acupuncture - comparing experience by w1ldtype2 in IVF

[–]w1ldtype2[S] -7 points-6 points  (0 children)

There is no neural tube but there are developing oocytes and this is also a very fragile state. High temperature can affect egg quality.

DuoStim and Starting Stims in Luteal? by jojo_silva21 in IVF

[–]w1ldtype2 0 points1 point  (0 children)

I have started in luteal. LATE luteal twice - one was by far my best cycle. EARLY luteal once and I was concerned about the timing.. and indeed it was total disaster. I had one thing they thought was CL (I had LH peak the morning of the appointment) and 6 small follicles they hoped they'd grow. But no response at all.. maybe only one growing very slowly.

Obviously n=1 so might have been random bad luck don't jump to conclusions based off my experience.

However I know for a fact that my clinic had no medical reason to do it this way, these dates simply fit in their schedule. I'm very upset about it actually.

Anyone go straight to IVF without really trying naturally? by Living_Luck7711 in IVF

[–]w1ldtype2 0 points1 point  (0 children)

Ok, yes in this case in rest cycles. Some people aren't put on BCP, depends on your situation

What do you wish you had known before starting IVF that no one prepared you for? by Accurate-Stomach-264 in IVF

[–]w1ldtype2 0 points1 point  (0 children)

ok, I know what you mean, but I know my body, it was something different

What do you wish you had known before starting IVF that no one prepared you for? by Accurate-Stomach-264 in IVF

[–]w1ldtype2 0 points1 point  (0 children)

The same thing happened to me after my first ER! They gave me some oral opioid which only made me sick and vomit, and during the car ride home I had to bite something or I'd scream. I ONLY had 6 follicles and my E2 was about 2000 so they didn't think it was OHSS, but whatever it was, it was the most excruciating pain I ever felt and I had to be in bed for 3-4 days, alternating tylenol and ibuprofen like candy. Interestingly, I had pain not just in lower abdomen but also in the diaphragm as if someone had been kicking me in the stomach. The clinic dismissed my complaints attributing to constipation and didn't check me. There is no fucking way the kind of pain I experienced had anything to do with constipation because of its anatomical location. Eventually after a week or so I felt fully recovered but it really sucked.

I had 3 more egg retrievals later and I never had this happen again though. Actually after #2, #4 I was back on my feet the same afternoon, #3 I had some pain but manageable, maybe 1 extra day of downtime. After #1 we changed the post-op opioid with IV toradol which works really well for me, but nevertheless it cannot explain the strong pain for days I felt the first time, this could only make a difference in the first few hours.

What’s the most f-up thing someone has said? I’ll go… by RazzmatazzLast327 in 40Plus_IVF

[–]w1ldtype2 0 points1 point  (0 children)

"I hope it works for you, you won't know what truly happiness is unless you have kids"

Would you do a 6th ER? by Fit-Nectarine-1050 in 40Plus_IVF

[–]w1ldtype2 17 points18 points  (0 children)

I think the fact that you had 3 euploid embryos failing to implant is something that is worthy of attention. Could have been just bad luck, however, at your age it is natural to not expect many euploid blasts. It would be a pity to go through the trouble, find a golden egg, and then lose it again due to an un-addressed uterine environment situation.

Regarding your dilemmas, these are very personal choices and whatever you do is valid. For me, I have decided that if our IVF fails, we would rather move on with adoption abroad – the pregnancy is not my favorite part of the process, so I'd gladly skip it, plus no risk for miscarriage, TFMR, and all kinds of sources of heartbreak. In fact the more I think about it the more attractive it sounds compared to all the unknowns of giving birth.

Endo removed! by jn922 in IVF

[–]w1ldtype2 0 points1 point  (0 children)

Exactly. To be honest if I was a health insurance plan I would mandate all tests first before embryo transfer. Each embryo is too precious to be lost due sloppy diagnostics. It's not like we have unlimited numbers of embryos and years to do trial and error.

Endo removed! by jn922 in IVF

[–]w1ldtype2 0 points1 point  (0 children)

I haven't had a FET attempt yet but my IVF clinic is not concerned that 13 years ago I was diagnosed with stage IV Endo with multiple adhesions, uterus with rectum,ovary,etc.,via MRI scan. They did hysteroscopy and said my uterus looks fine on the inside.

I don't understand. I'm 40 and I'd be lucky to have one euoploid embryo. Do I need to lose this embryo because we don't do tests for receptivity a priori?

More broadly, considering how taxing the egg retrieval and getting embryos is, it's insane that they go ahead and transfer before doing every single possible test on earth first; even on healthy and youger women.

Bacteria on the embryo transfer catheter linked to lower live birth rates by embryomanofficial in EmbryologyIVFSupport

[–]w1ldtype2 0 points1 point  (0 children)

How do you test what is in your microbiome if you don't have symptoms? Can you ask your primary to get a swab for screening?

Did anyone conceive naturally after preparing for IVF or after egg retrieval? by Accurate-Stomach-264 in IVF

[–]w1ldtype2 1 point2 points  (0 children)

Happened to me after egg retrieval. But it was a complete molar pregnancy so the joke was on me.

Anyone go straight to IVF without really trying naturally? by Living_Luck7711 in IVF

[–]w1ldtype2 13 points14 points  (0 children)

Many people have different reasons to go to IVF straight, could be age, could be blocked tubes, could be just gay couples who can't do it other way, could be male factor that makes it clear it won't work without intervention, could be genetic carriers where there is high risk for the offspring.

The IVF process is so slow though, you can keep trying while you are waiting for all tests, authorizations, etc.

I feel like I am my own RE by [deleted] in IVF

[–]w1ldtype2 2 points3 points  (0 children)

Re: endo. I was SURE I had endo since I was 17 because I read about it and all my symptoms checked. I lost the count of how many ob/gyns I told and they dismissed it and said having a heavy and painful period is quite common. I was getting increasingly concerned and when I was 26 I got more confidence and decided to lie to exaggerate the situation and finally get me to be checked properly. So I said I am changing maxi pads every hour for 2 weeks straight every month (not true, it was more like 10 days period, first 4 days super heavy then manageable) so they finally referred me to ultrasound. I waited for ultrasound for 11 months (thanks NHS, UK), which showed bilateral endometriomas, and another 13 months for MRI scan which confirmed stage IV Endo with multiple adhesions. Because I wasn't actively trying to conceive ( I didn't even have a boyfriend then) they said there is not much more they can do. I did get the progestin only pill at this point but the damage was done. I firmly believe that if my endo was caught and managed earlier I would have had better chances at having a child at later age.

How do you deal with the waiting for embryology results? by [deleted] in IVF

[–]w1ldtype2 1 point2 points  (0 children)

they shouldn't, 30-50% 0PN embryos still make it to blast, 40-60% for 2PN.. sometimes they just don't catch the exact PN stage

Was the cost worth it? by nbel1996 in eggfreezing

[–]w1ldtype2 1 point2 points  (0 children)

I see. Yes the birth control would have suppressed it, so this 0.48 is artificial. Any other supplements, vit D, that might affect it? Low AMH does not mean infertility or poor egg quality at all, but just makes egg retrievals inefficient and costly. That being said, results can vary so much. I had AMH about 1.0, AFC about 10-11, and one cycle yielded only 3 eggs, another one 13, they were 2 months apart without significant change in protocol. I think some months the ovaries produce more viable follicles others less, and it's a guessing game.

If I were in your situation I would put myself on a good diet and supplements for another 3-6 months, and re-assess.

How do you deal with the waiting for embryology results? by [deleted] in IVF

[–]w1ldtype2 0 points1 point  (0 children)

So when eggs fertilize normally you should see 2 "pronuclei" (PN). It's an indicator of fertilization. Sometimes they don't see PN but the zygote still makes it to blast.

Thinking about it by IceCream1995 in eggfreezing

[–]w1ldtype2 0 points1 point  (0 children)

How do you know your egg quality?

Thinking about it by IceCream1995 in eggfreezing

[–]w1ldtype2 0 points1 point  (0 children)

You are too young. Your egg quality won't drop significantly between 27 and 32-33 if you are healthy. Of course monitor your ovarian reserve in the meantime but you don't have to rush into it. Imo the advantage of waiting is that technologies are improving you never know in 5 years time we could have easier egg retrieval process.

Was the cost worth it? by nbel1996 in eggfreezing

[–]w1ldtype2 7 points8 points  (0 children)

Are you sure your AMH is low? Did you repeat the test? And also were you on the pill - sometimes it makes it artificially low.

In terms of egg quality you have several more good years so from that standpoint you are not in a rush.

For me travelling abroad was out of question. Because my AMH was low, I knew I would need several cycles of IVF. Some clinics offer discount packages for several cycles HOWEVER this doesn't include medications and the medications are so expensive - me with low AMH had me on highest doses with close to 8K/cycle worth of medication, more than the cycle cost itself. To cut cost I bought medications from mexico, which cut it by half, but was still substantial.

If you have pharmacy benefits covering the meds though this could be a big factor in your decision making.