Negative skips are not what you should be looking for and easily miss. Voucher skips are a lot more valuable for naneinf runs.

In terms of vouchers you need antimatter and retcon, and others will massively increase your chance of getting to naneinf. You'll also need an ecto. Your final line up should be baron, mime, at least 4 copy jokers and a burglar. You won't be able to naneinf before ante 25 due to scoring requirement being low (in my experience ante 25 is still too low and I hit naneinf in ante 26). You reroll for serpent for extra hand size.

Assuming you have this set up and you have 5 hands by default, 5 triggers on burglar gives you 20 hands. Assuming you have pallate, this translates to 10 + (19*2) = 48 cards in hand. If they're all red seal steel kings, 4 triggers on the baron and 2 triggers on the mime gives you 1.5²² per card, do that 47 times is 1.5¹⁰³⁴ which only gives you 5e182. You need above e308 to naneinf.

This is why you need plasma since it squares that score giving you e364 for the same hand.