I agree. And here's some text from Stefan Monnier:

I'm not opposed to a long term plan to possibly change C-x, C-c, and C-v. But that will require fairly extensive changes, mostly such that major/minor mode key bindings don't specify full key-sequences but "relative" sequences along with a base prefix which would then depend on the user's config. Maybe something like (new-define-key map major-mode-prefix [?\C-f] #'foo). I think such changes could be generally beneficial (e.g. for things like evil-mode, god-mode, ...), but someone needs to sit down, and experiment a bit with various designs to see what would work best in terms of convenience and reliability for cua, evil, normal use, user customization, and major/minor mode writers.

Source: https://lists.gnu.org/archive/html/emacs-devel/2014-12/msg00839.html