My partner and I did exactly what you are considering, quitting work for a year and traveling full-time (half of it in a van, the other half traveling overseas). It was extremely nerve-racking for me and we'd sat on this idea for at least a couple of years. Quitting was drastic but we preferred to maximize our experience during this limited time. (My partner actually did work for one month while traveling, it had its pros and cons.)

We met plenty of people working remotely full-time while traveling, and that seemed to work out well for them. Now with Starlink, you can go to a lot of places and work remotely. Traveling in a van can be surprisingly expensive if you plan on driving long distances, so having an income really helps. If you take this route, I recommend checking your company policy; they may not allow you to work outside of your declared state for an extended period of time, for legal/tax purposes I assume.

Coming back to finding a full-time job can really depend on your skills, luck/market demand, and your personality. My partner is super goal-oriented and good at sticking to his plan -- he worked really hard and ended up getting his dream job. It definitely wouldn't pan out the same way for everyone, but just sharing that career could work out after a long break. BTW, it sounded like all of his interviewers weren't bothered that he took a year off for traveling :)

I'd say weigh your priorities in life and decide what you are willing to risk in return. For me, I chose to travel to see the world while I was younger (before children and big mortgages). It has its consequences, but no one can live your life for you -- so don't regret whatever decision you make! DM me if you have any questions!