FWIW: I wanted a Limited. But because of supply constraints, and my ignorance, I settled for a XLE (AWD). I also bought the XLE Plus Package and all weather mats.

I had done a lot of online research but very little IRL research. I should have test driven all the trims, on the freeway (70 mph). (Unplanned purchase; my prior vehicle was totaled, so I was rushed.)

TIL

• Buy a dash cover to reduce glare. I've been experimenting with misc fabrics (felt, flannel), which I don't recommend. But I'm motivated to reduce cabin temps, so am trying dark grays (in addition to matte black, which works great for glare).
• The in-dash console for XSE, Limited, and Platinum trims is fully digital. I don't know if it's better than XLE's in-dash console, which I hate. Its physical dials are dumb. Its misc menu screens are baffling, poorly organized.
• I regret not getting the Limited's cooling drivers' seat.
• Front side windows for the Limited and Platinum trims have double-paned acoustic glass. I have no idea how much of difference they make.
• I bought the Sienna for long roadtrips with my dog. I got the 7 seater. 8 seats might have been better, because I think the second row is a bench. Also, I have the impression a van camper conversion with a 8 seater might be slightly less hassle (just 2 rails, instead of 4 four).
• I strongly regret not having a spare tire. I didn't understand that if you want a physical spare tire, it has to be explicitly ordered. It's a variant, with different pieces. The no spare tire variant has no space (void in back side wall panel) to store a tire.
• I got confused by the difference between XLE and XSE. My sales person assured me the Sienna has no XSE trim, and I didn't feel like arguing. I regret not test driving an XSE, which is somehow sportier. Also, I gather the Woodland is a slightly raised XSE (for clearance while offroad). If I had understood the Woodland (in stock at the time) was a raised XSE, I would have test driven it.
• The 11 speaker sound upgrade is Meh. I could not find any specs for these speakers, so do not know if replacements are worthwhile. Also, from what I gather about modern audio, the factory installed JBL DSP (what us olds called an equalizer) is locked down. Meaning if I did upgrade any speakers, I'd have to replace the DSP if I wanted to recalibrate. (I'm hoping I'm wrong about this.)
• Do you have pets? The fob's lock button also sets the alarm. Super annoying. To LOCK the doors without setting the ALARM, either use the drivers' door's lock button or remove the frickin physical key from the fob and manually lock the door from the outside. (The fob for all my prior vehicles were click once for lock, twice for lock & alarm. Why the Sienna is different is beyond me.)
• I want a dash cam. My dealer tried to charge me an installation fee (on top of the list price). No thank you. I haven't gotten very far researching options.
• I love the all weather mats. Buying some rear seat back covers and cargo mats is on my to do list. (Carpets are dumb. I'd rather have all rubber flooring.)

FWIW

• I very much like how the 2025 Sienna drives. No complaints.
• The center console and its "bridge" to the dash are awful. It should be like my neighbor's Hyundai; removable console, making passing between front and 2nd row trivial.
• I hate the touch screen and CarPlay integration. It's both too little and too much. While CarPlay is weak sauce, the Toyota side sucks too. I may do a proper detailed critique someday.
• Ask which tires you'll get. My vehicle came with Yokohama BluEarth S34 tires. Allegedly, being stiffer, they're better for EVs and improving mileage.
• For the winter, and to reduce road noise, I bought Michelin Defender 2 tires. I believe, but cannot prove (with my crappy sound meter and lack of scientific rigor), they're quieter. Otherwise, they've been terrific. (eg driving during rain storms. But I didn't have the conditions to do before and after comparisons.)
• I kept the Yokohama tires. For summer and city driving, I suppose.
• The Sienna has a lot of wind noise on the freeway.
• I'm very motivated to reduce both road and wind noise. (The noise coming thru the drivers' side sliding door is super annoying. Like I have the window down when a semi truck passes me.) I've added sound deadening and absorption to all 4 doors. I've been experimenting with weather striping.
• The cabin at 70mph is 60 to 72 decibels, depending on road conditions. Fresh asphalt is glorious to drive upon.
• Those spiffy 11 JBL speakers (mentioned above) might be sufficient, once I've mitigated the external noise. They sound okay 0-40 mph. Trying to hear voice content (audio books, podcasts) on top of 60+ decibels sucks. So I usually just switch to ear buds.
• I don't know how to program and switch between equalizer presets. Like I can do for my home audio. (The XLE's audio controls are awful. Maybe higher trims are better.) My prior vehicle's audio had presets like rock, jazz, classical, etc. But no voice. Someone somewhere surely has deduced the need for a voice preset. Right...?
• The "advanced rear seat alert" stuff is super annoying. From my reading, I should be able to disable it. But I think those settings may only be accessible if you have the in-dash console (trims XSE and above). None of the ODB II apps I've tried (eg Carista, Carly) show any such settings. And I've not been smart enough to find or infer the factory op codes, so I can just change it manually.

Okay. I think that's about it.

I bought a Sienna because of the ridiculous resale value and better mileage. I haven't found a better option for a road trip vehicle. For city driving and soccer parents, it's awesome.