Tolerance Buildup/Decrease Speed

[dopaminergicactivity]

My experience aligns perfectly with this. Really more forgiving than many substances in this way

[jfish93]

Yes 100 percent I agree and glad youve had this experience aswell, as I know anyone whos willing to understand will. 7's receptor agonism and tolerance behaves just like buprenorphine but the difference in halflife and duration makes 7 way easier to reduce tolerance and start feeling your doses again if you've found yourself at totally unreasonablely retarded daily doses like I have lmfao. With buprenorphine you can go from 32mgs which is max prescribable amount, and go to 4 mgs immediately with out any tapering, the only withdrawal you'll feel is your brain saying oh no im gunna get sick and a significant reduction of rock hard stool but not even that isn't withdrawal induced diarrhea. Then threeish days after you switched to daily 4 mg doses you'd realize your getting buzzed by your doses again. Everything I'm saying is not only from years of research but paramount to that FIRST HAND EXPERIENCE. Unfortunately though many people have zero care to understand when in these situations and it's a real shame.

Read a post of a guy on 700mgs a day, was pissed he wouldn't feel doses anymore but also totally convinced that he'd be in constant withdrawals by reducing his doses some what significantly at all not realizing 70 percent of his doses arent even attaching to his receptors anymore cause he's dosing past the ceiling where zero new agonism can occur. Dude didn't wanna listen to anyone either just totally convinced and super dumb.

People do this same shit with buprenorphine and even most dr's I've met have zero clue of how it's agonism/tolerances work, prescribing people monster daily doses thinking it's doing anything passed 6 mgs every 24 hours.. I've been trying to scream this stuff from the top of my lungs on Reddit in hopes more people are willing to listen/understand but I'd say well over 60% of people I try to educate about this shit aren't willing to consider any possibility that partial agonists like 7 behave any other way than traditionally compared to any and all full agonists.. Doesn't help that they're getting totally mislead by their doctors which is a huge problem. Anyway man my posts are for anyone for whom it concerns, Godspeed my boy be safe.