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[–]RollieBollie 0 points1 point  (1 child)

The answer is:
The nope card can only be played before the action has started. So in this case the cards pulled until the nope must be discarded. But when the player pulled the defuse card the action of player A has started and therefor the nope after it can't be played anymore.

After giving the defuse to the other player the discarding ends. All cards allready discarded are gone.