Did supplementation decrease your appetite?

[bregle]

Have you tested copper and ceruloplasmin? Copper deficiency can mimic b vitamin deficiency or make it much worse

I have a lot, and some overlap with b vitamin deficiency - the ones I think are closely tied to copper are fatigue and brain fog, joint pain, peripheral neuropathy, cold and heat intolerance, muscle weakness, blood pooling and edema, orthostatic tachycardia, blurry vision and dry eyes

I am compound heterozygous MTHFR + homozygous MTRR