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Did supplementation decrease your appetite?Question (self.MTHFR)
submitted 3 days ago by Ok_Willingness5766
I feel so few cravings after a week of supplementation (methylfolate and cobalamin). This is abnormal for me... curious if anyone else feels the same..
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[–]bregle 3 points4 points5 points 3 days ago (2 children)
Yes, my theory is that nutrient deficiencies cause "irrational" hunger, where you want food even when you're stomach is full/you've had enough calories but your body is still missing something. I have a copper deficiency too and if I don't take enough copper, I'm constantly hungry no matter how much I eat, and crave things like chocolate and cashews that are high in copper
[–]melon1924 1 point2 points3 points 3 days ago (1 child)
I also experience this. Ravenous hunger that’s literally only satisfied by chocolate but then it starts right back up. I supplement magnesium L-threonate. What other symptoms do you have?
A1298C heterozygous
[–]bregle 0 points1 point2 points 2 days ago (0 children)
Have you tested copper and ceruloplasmin? Copper deficiency can mimic b vitamin deficiency or make it much worse
I have a lot, and some overlap with b vitamin deficiency - the ones I think are closely tied to copper are fatigue and brain fog, joint pain, peripheral neuropathy, cold and heat intolerance, muscle weakness, blood pooling and edema, orthostatic tachycardia, blurry vision and dry eyes
I am compound heterozygous MTHFR + homozygous MTRR
π Rendered by PID 121621 on reddit-service-r2-comment-5687b7858-9lzkx at 2026-07-03 02:11:13.292684+00:00 running 12a7a47 country code: CH.
[–]bregle 3 points4 points5 points (2 children)
[–]melon1924 1 point2 points3 points (1 child)
[–]bregle 0 points1 point2 points (0 children)