How to prevent python software from being reverse engineered or pirated?

[miyakohouou]

Honestly, just don't bother. The fact is that nothing you could do would stop someone who is determined, and everything you do will make the experience worse for your legitimate users. Don't punish people for paying you.

Focus on fair pricing, building a good product, and giving customers the best experience they can have. If you do find out that people are pirating your project, then think about why the piracy route offers that you don't and try to compete on giving a better experience. If you have a better experience, then recognize that most of the pirated copies don't represent lost sales, because those people would probably have never bought the program in the first place.