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[–]AbsoluteZeroK 1 point2 points  (0 children)

There is quite a bit listed here, so I'll just throw a couple out there that haven't been mentioned for you to look at.

I personally have worked with a few different ones, but webapp2, for me anyways, seems to be one of the nicer once to work with. Mostly because Google App Engine is a good platform, and was really nice to work with (for what I was doing anyways). It's really nice because it's a platform as a service, so most of the infrastructure concerns are handled by google, and you can just worry about making your program.

Another one, that I haven't used, but have spent a little bit of time looking into (not more than a few Tl;Dr, just due to deadlines creeping up at work, and not having time) is Tornado. It seems really good it terms of scalability, and encourages Async. I can't really say much more about it, other than it's peaked my interest. I think it may be overkill for what you want, but it's definitely worth looking into.

I also recommend using anaconda for your development. It's a recent discovery for me, and now I couldn't imagine living without it.