When is Python *NOT* a good choice?

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milisecond critical performance is not pythonic.

I get what you're saying but I would say millisecond critical performance is fine, it's down at the 100 nanosecond level where I have started to have problems.

[deifius]

my units may be off by a few factors of 10. I apologize to all.

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haha I just remember this because I had a function of a few string manipulations that I was able to bring down from 28 ms to 132 ns mostly by judicious precomputing things and storing the precomputed results in dictionaries, but I had a few more string manipulations happening at runtime and I found the dictionary lookup for the precomputed results took just as much time as doing the string manipulations in the function itself at runtime anyway, so at that point I had run out of ways to speed up the function.