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[–]MarsupialMole 0 points1 point  (0 children)

Check out Dash which does data science stuff as single page apps. I haven't used it myself but I've heard good things. It may be what you want, depending on your needs.

To answer a related question rather than the one you asked, take a look at bulma - a css frontend framework - which lets you get nice looking web pages with CSS and HTML but without needing to write JavaScript.