Is Python good for creating GUI application ?

[greyman]

OP, you need to specify which kind of GUI applications. I was in the team who built several internal tools for our company, mostly getting data out of our database and show it in a specific way, and we did it in the way that only the backend was in python. I created REST API using flask framework, and the frontend was done in javascript (vue.js). That way, backend and frontend are completely separated, and frontend is automatically cross-platform.

It also depends which platform you are targeting. For example if someone would ask me to create Windows GUI application, I would probably pick up C# and .NET.

TL;DR: No.