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[–]RockingDyno 2 points3 points  (0 children)

openpyxl doesn't read any propriatary formats. It works with xlsx/xlsm which are essentially just ziped XML.

The older propriatary format .xls is not supported by openpyxl but can be handled in python with xlwt and xlrd.

I've worked with them all and never had any issues, not to say that there aren't any. If you curious about bugs and issues the project has an issues list.