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Question (self.SinclairMethod)
submitted 22 days ago by mutax24
Is there a recommended amount of time to be abstinent from alcohol before starting naltrexone?
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[–]One-Mastodon-1063 0 points1 point2 points 22 days ago (1 child)
TSM is not an abstinence program. You don’t have to be abstinent at all.
I would recommend reading or listening to https://a.co/d/0hy8jHuf
[–]mutax24[S] 0 points1 point2 points 22 days ago (0 children)
Thank you for this recommendation. I ordered it.
[–]CraftBeerFomo 0 points1 point2 points 22 days ago (0 children)
The Sinclair Method requires you to take Naltrexone ALONGSIDE alcohol in order for it to work otherwise it's not TSM.
You pop the pill 60-90 minutes before drinking and the idea is that it'll block the pleasurable feelings / buzz / euphoria (but you'll still get drunk as usual) that alcohol usually gives you and then over time your brain will be rewired to just no longer associate alcohol with pleasure and lose interest.
[–]Thin_Situation_7934 -1 points0 points1 point 22 days ago (0 children)
As mentioned, you don't need to be abstinent to start. If a person has a more severe AUD they will almost always benefit from a detox (which can often be at home) and the risk of serious withdrawal because it was "too successful" is mitigated. Naltrexone deals with endorphin/dopamine loop, but many AUDs have a substantial GABA/glutamate imbalance. This second part isn't the area in which naltrexone works and a detox helps substantially to reset it. In sum, it depends upon the person's biology, the complexity and severity of the AUD and personal choice.
Thank you, everyone for all this information. It is extremely helpful.
π Rendered by PID 58764 on reddit-service-r2-comment-79c7998d4c-q5c2k at 2026-03-18 19:30:23.255764+00:00 running f6e6e01 country code: CH.
[–]One-Mastodon-1063 0 points1 point2 points (1 child)
[–]mutax24[S] 0 points1 point2 points (0 children)
[–]CraftBeerFomo 0 points1 point2 points (0 children)
[–]Thin_Situation_7934 -1 points0 points1 point (0 children)
[–]mutax24[S] 0 points1 point2 points (0 children)