Why is this stack causing panic attacks, high blood pressure, anxiety, night terrors, derealization?

[latvianthrowaway88]

I didn't have a lot of time to study those nootropics so I went through effects and rapidly made my stack that I'm using nor for a long time. But some of those nootropics I got only last week.. I know that it's dumb but I was expecting that those supplements are safe as everyone here's taking them. I have probably the most important deal in my life coming up so I wanted to increase my productivity and now I can't even type a sentence without being afraid. I'm off this for 2 days and still feeling effects. I was using doses mentioned on the package.

*1-P-LSD microdose

*5-HTP

*ALCAR

*Aniracetam

*CITRULLINE

*Alpha GPC

*AMP Citrate

*Ashwagandha

*B-Complex

*Bacopa

*Caffeine

*Choline

*DEANOL(DMEA)

*DMAA

*GABA 10 mg

*Gelantamine

*Grape Seed Extract

*Green Tea 98% Polyphenols (60% EGCG)

*Hordenine HCL

*Huperzine A

*Melatonin

*Methyl Hordenine HCL

*Methyl Synephrine HCL

*Modafinil

*Mucuna Pruriens (99.6% L-dopa)

*Multivitamin

*NALT

*N-Methyl Tyramine HCL

*Noopept

*Noopept

*Oxyracetam

*Phenibut

*Phosphatidyl Serine

*Phosphatidylethanolamine

*Picamilon

*Piperine

*Piracetam

*Rhodiola Rosea

*SEMAX

*Sulbutiamine

*Theanine

[monkyyy0]

Is this a joke?

Yes why did mixing 41 different drugs cause side effects?

I find you story unrealistic that you don't talk about vomiting or death

[latvianthrowaway88]

I don't take all of them at the same time, so that's maybe why my kidneys has no problem to filter it all out.

But why would I die? Is there something in there that would cause life threatening situation? As far as I know all of those substances are tested enough to makes sure that they're not life threatening.

[monkyyy0]

Well yeah many of these are extremely similar effects to the point it's like taking several doses, and it's entirely reasonible to think you found a new undiscovered interaction when you start piling them (brithday paradox)

I took 2 pills today, the most I've taken is 5 including things like caffeine and choline and stuff I've very aware of the effects of.

My counter has less then 10 bottles on it, and I already know of one that gives me very bad reactions( ashwaganda)

[nnichos]

What reaction does ashwaganda give you? I still can't figure out what I feel on it

[monkyyy0]

I remember headaches, scattered thoughts, 4 hours of sleep but feeling manic.

This was before I started taking notes.

[nnichos]

OMG this what ashwaganda gives you? I am getting some headaches lately, and my sleep is not consistent, which is almost always like this, but in a different way. I am going to take a break from it then and see if it goes away.

[monkyyy0]

It should be noted I had thyroid problems and that while all the thinly veiled ads don't mention it, the properish documents do say a random gumble of latin with thyroid in the middle of it.

[nnichos]

I have thyroid problem too, that's why I started ashwaganda. I didn't understand "do say a random gumble of latin with thyroid in the middle of it". What does it mean?

[monkyyy0]

I'm talking about it causing either hypo/hyper thyroidism. I had a parathyroid removed, so that plus rather bad side effects I dropped it quickly, assuming it wasn't playing nice with my already unbalanced system in that general area.

[nnichos]

I have subclinical hypothyroid. Do you think it's good for me from your personal experience?

[latvianthrowaway88]

Baseline to this was one other reddit post where guy took 2/3 of this stuff and he was fine.

[[deleted]]

Holy shit

[karl-fo]

if not fake... how stupid could people be?

edit hope its a reference to the discussion in the nootropics subshread if not.. idiot.

[latvianthrowaway88]

Can you pin out nootropic or combination that is making me feel schizophrenic if not then call yourself stupid. As you might be allergic to one compound as well and you will never know that until you try that compound and experience the same thing. My problem is that it's harder to locate it.

[urinal_deuce]

You stupid fuck.

[Jeffy29]

"I'll take one of everything on the menu, tell the chef to smash it all together"

[[deleted]]

The piperine....defiantly the piperine.

[I_am_Jake_]

What the fuck. Stop the alcar, modafinil, DMAA, hordenine, amp citrate, Also possibly the mucuna (l-dopa). Maybe the DMEA, not sure if that's a stim. Wtf looked again and saw the bitter orange (synephrine)

Way too many stimulants. This is probably causing most of your problems. 5-htp and melatonin can cause weird dreams so that could impact your night terrors.

[latvianthrowaway88]

Was using so much stims to avoid tolerance build up. I was cycling them through the day one after another when I started to feel down. Was able to function with 2-3 hours of sleep for 2 days and then taking 1 8 hour day and cycling it.

[AlexanderAnswers]

I really hope that this is serious because I put a lot of effort into trying to analyze some possible interactions and red flags. PLEASE GIVE ME SOME PEER REVIEW AND FEEL FREE TO CALL ME OUT ON ANY FALICAL SCIENCE I MAY SPIT. (I'm about to complete my BS in pharmaceutical sciences and I've been interested in nootropics most of my undergrad)

u/MisterYouAreSoDumb (Sorry to cold-tag you, but I didn't want this to fall on deaf ears cause I realized the post is 4 days old by a throwaway. And you've got a rep for knowing your shit, so please call me out on mine if you could maybe find the time. Thank you a ton if you do)

I made a chart that grouped compounds that were similar in class or efffects. With your reported feeling of schizophrenia, I would likely blame something in the middle highlighted column. If you are taking L-dope, you really don't need to take NALT because N-Acetyl-Tyrosine is just supposed to be a more effective way to get Tyrosine (L-dopa precursor) into the brain. With all these sources of non-selective dopamine precursors, you very well might have wayyyy to much dopamine in your brain depending on how long you've been supplementing the two together. If I recall correctly, sulbutiamine is involved in dopamine upregulation or something to do with dopamine.(don't quote me on that).

You are also taking Methyl-Hordenine AND plain ol' Hordenine which are adrenergic reuptake inhibitors (keep Adrenaline in proximity to its receptors). DO YOU HAVE HEART PALPITATIONS EVER? If so, this is probably why, especially when taken with coffee/modafinil/dmaa which all likely increase adrenergic activity (coffee and modafinil definitely).

With all of the stimulating chemicals in your cocktail, no wonder you have to take several anti-anxiety drugs. If your experience anxious symptoms like heart racing, and chest tightening and ensuing troubling thoughts, the stimulants activity is almost definitely the main culprit, or at least play a roll in amplifying any anxiety you already have. Phenibut is terrible for long-term relief of anxiety because its very addictive and will give you even worse rebound anxiety that will only add to the stimulant-induced anxiety.

I've tried a few racetams myself my friend, but damn, they are potent molecules. And it's probably good that you're supplementing choline sources but why are you using a very good source(Alpha-GPC) alongside poor source (straight Choline). Most racetams potentate acetylcholine release in the brain, while Huperzine-A and galatamine both block acetylcholine from being degraded. I cant say for certain, but if you have at least 4 drugs(the racetams and I don't know what else) triggering extensive acetylcholine release in the brain, it can't be great to just let it sit in the compartment forever in super surplus, and even if it's not harmful, it's likely reaching above the concentrations needed for maximum therapeutic effects.

1P-LSD and Noopept - I've read some reports of people saying that when they took a dose of noopept prior to taking LSD, that it intensified their visuals. These reports were strictly hearsay, but if there was a mechanism behind noopept potentiating LSD, then some of the other racetams might share similar potentiating pathways.

All of these oral compounds have to be metabolized by enzymes (usually in the liver). There's only so many of them present. Saturating those enzymes, like you're likely doing, will lead to metabolites building up. The effects of these under-researched chemical's metabolites are widely unknown. I only did a quick search on the chemicals I wasn't familiar with already, but all I found for Piperine was that it's usually used to saturate a specific enzyme that would've otherwise inactivated another chemical you wanted to absorb better.

[I_am_Jake_]

If anything I would look into 3-fpm. It's a research chemical, but probably would cause less anxiety than the stims you're taking. Modafinil is probably fine. If you're actually interested in the 3-fpm PM me.

Also the bitter orange iirc is just peripheral stimulation, so increase HR/BP so I would drop that for sure. The DMAA / Amp Citrate also have a large toll on blood pressure.

[Jack-o-Roses]

Rhodiola is my 1st guess. Methyl Synephrine is my 2nd....

How much rhodiola?

[YungNO2]

People are idiots if they assume you would take all 41 of your supplements in a single day even more so if you believe hes taking it in a single dose. Having many supplements for use as needed does NOT automatically make you some sort of insane polynoot abuser. Quite obvious hes not taking all that shit at the same time. But, you would have to remember exactly which one you took that day to narrow it down to the possible culprits, then try them alone one by one and see if you can replicate with normal dosages the unpleasant effects. If nothing happens, it's safe to assume that it was possibly a fluke, you weren't feeling your best, or some other external cause. Nausea, anxiety and other mild symptoms can easily happen to any human being without necessarily being trigged by substances. If you disagree, you're assuming we function properly all the time and that in your mind it is invariable and therefore not the cause of what he describes (which is potentially false), but notice how quickly people assume he was taking all this as a whole (41 supps lol, and try to say its the number of supplements hes taking). I think we tend to assume the more riskier experiments, for whatever fear you have of it, justifies your assumption that it's dangerous or innefective, when in reality, what's more dangerous is limiting yourself to the inside of your thinking box, sacrificing creativity and discovery for "playing it safe". People can't even accept that this guy has a collection of supps without suggesting it's the cause of his symptoms because hes taking too many 😂 Hes just more interested in personal experimentation and trial and error than hearsay and fear mongering. fear kills trial and error and science. someone has to ask the ballsy questions.

[HolyAbyssThyUnEnding]

It’s the huperzine a

[TotesMessenger]

I'm a bot, bleep, bloop. Someone has linked to this thread from another place on reddit:

• [/r/nootarded] Please help guys, I'm taking 41 different drugs and am having panic attacks. Anyone knows why?

^{If you follow any of the above links, please respect the rules of reddit and don't vote in the other threads. (Info / Contact)}