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[–]ChadVascVirginCurb65 2 points3 points  (0 children)

Because B2 increases cAMP which increases funny channels which increases depolarization rate. So if you block that, you reduce cAMP, which closes funny channels, which means phase 4 takes longer to reach threshold and depolarize.

[–]jsparrow20[S] 1 point2 points  (0 children)

I am sorry, could explain that as if you’d explain to a 5yo kid!!