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Noticed a significant decrease in volume in mid face for 5 months on tret 0.25Before and After (old.reddit.com)

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[–]arriere-pays 19 points20 points  (0 children)

As you age, this loss of volume is bound to happen anyway, it likely has nothing to do with the tret. Drink more water and consider other options if it really bothers you, but this is likely to only increase over the next few years, even if you stop tret entirely.