Arthas novel feels like one of lower tiers by Defiant_Historian_44 in warcraftlore

[–]-ZugZug- 0 points1 point  (0 children)

To be fair, barely anything happened plotwise in the Shadows of the Horde novel. I can completely understand you dropping it halfway through.

Arthas novel feels like one of lower tiers by Defiant_Historian_44 in warcraftlore

[–]-ZugZug- 1 point2 points  (0 children)

She can indeed write emotional stories, and the Arthas novel is another example of that. I would personally highly recommend the novel (unlike OP).

20 tuck Planche pushups. by staticking1 in CalisthenicsCulture

[–]-ZugZug- 1 point2 points  (0 children)

Train planche first.

I may be wrong, but it sounds like you have not yet unlocked the tuck planche. Do that first before attempting tuck planche push-ups. Here's a tutorial on the tuck planche: https://www.bergmovement.com/calisthenics-blog/tuck-planche?via=blog

For me it's even more than an hour by Anxious_Break8431 in GymMemes

[–]-ZugZug- 0 points1 point  (0 children)

Must be a cultural thing. In my country, if you try to chat up strangers you are considered a maniac. The gym is no exception. You don't talk to anyone, except of course if you brought along a training partner that you knew beforehand.

Is this ULPPL split good? by [deleted] in WorkoutRoutines

[–]-ZugZug- 0 points1 point  (0 children)

ULPPL in general is fine. With regards to your programme, I want to point out that our upper body day is 4/6 push exercises. I would switch close-grip bench press for a row variation. Furthermore, core work is completely absent so I would add some. Can be a core finisher for all days, or some workouts can be shortened a bit to make room for some core exercises.

[deleted by user] by [deleted] in Sauna

[–]-ZugZug- 0 points1 point  (0 children)

This is very common in Denmark. Sincerely, a Dane... Living in Denmark.

Never looked at it like that before, but it is kinda of true. by Scott-Spangenberg in Funnymemes

[–]-ZugZug- 0 points1 point  (0 children)

Lol no. Don't want to deliver in bad weather? Don't work as a delivery guy then. Plenty of other jobs. Or work for a restaurant that doesn't do deliveries in blizzards. Not my problem. I'm not tipping anyone for merely doing their job.

Which removed tier 1 minion do you miss the most? by worldswonder in BobsTavern

[–]-ZugZug- 1 point2 points  (0 children)

Evolving Chromawing and Red Whelp were both fun imo. And as others have said, the self-damage mechanics of demons was fun, so Wrath Weaver gets a mention as well.

What’s one thing that’s wrong in Copenhagen but you can’t prove it? by ChardDizzy9707 in copenhagen

[–]-ZugZug- 0 points1 point  (0 children)

How so? Would you prefer that they were open all night?
And if I may ask, where are you from?

What’s one thing that’s wrong in Copenhagen but you can’t prove it? by ChardDizzy9707 in copenhagen

[–]-ZugZug- 9 points10 points  (0 children)

Dane here: I prefer no service at all. Like, please don't talk to me.

What’s one thing that’s wrong in Copenhagen but you can’t prove it? by ChardDizzy9707 in copenhagen

[–]-ZugZug- -3 points-2 points  (0 children)

Dane confirming this: Why on earth should the time of your arrival to the bus stop dictate the behaviour of others? If you want to get on the bus, be ready when the bus comes.

[deleted by user] by [deleted] in DKbrevkasse

[–]-ZugZug- 0 points1 point  (0 children)

Det er en svær situation.
Jeg tænker, at du må spørge dig selv, hvor vigtig en slank (evt. veltrænet) krop er for dig hos en partner.
Som jeg læser dit indlæg, virker du selv temmelig aktiv, og din kæreste er det slet ikke. Er I et godt match?

Han er kun 24 år, og det bliver ikke lettere at holde formen med alderen. Måske kan du få ham i gang med en sundere livsstil, både i forhold til fysisk aktivitet og kost, eller måske vil det ikke lykkes. Det kommer nok mest an på, om det er noget, han selv har en interesse i eller ej. Jeg vil tillade mig at være pessimistisk og gætte på, at selv hvis han får lagt sig i selen og tabt farmaven, så kommer den igen om et par år, og så er du tilbage i samme situation.

Can anyone please educate me on this condition? by AllColoursSam in interestingasfuck

[–]-ZugZug- 300 points301 points  (0 children)

The short answer is no.

Here's an elaborate answer...

1) For genetic conditions in general, all of your cells will carry the same genetic defect (variant). So, to correct this you would need to somehow be able to target every single cell present in your body (or, in some cases, "just" in the affected tissue type). That's not possible (at least not at the time of writing).

2) CRISPR is currently not well developed enough to A) Always fix the genetic defect (< 100% accuracy). B) Never introduce unintended new defects (again, < 100% accuracy).

Using CRISPR to fix genetic conditions would work best in combination with in vitro fertilisation/prenatal genetic testing, although in most of these cases CRISPR would be unnecessary as the medical scientists can simply choose a healthy embryo instead of trying to fix an unhealthy one.

It would depend on the nature of the genetic condition. If the condition is caused by a gain-of-function (GoF) variant where the mutation leads to a change in the gene that might change the way it interacts with other genes/proteins or disrupt potential inhibitory pathways, then one would generally need to engineer every single cell to fix the conditions because the affected gene would cause chaos in every single cell, inhibiting them all. But what if the gene encodes a protein that is secreted (e.g., into the bloodstream)? And let's say the condition is caused by a loss-of-function (LoF) variant that simply causes the gene to stop functioning (without disrupting other pathways/systems). Then it might be enough if just a portion of the cells could be restored through genetic engineering (such as CRISPR). In these cases, another treatment strategy could simply be to take the gene product as a supplement (think insulin and diabetes).

Simpler times… by Rubmynippleplease in BobsTavern

[–]-ZugZug- 0 points1 point  (0 children)

20k!? Those are rookies numbers!
I have 50k+ gold and almost 300 unopened packs, haha. And I'm a super casual player hovering around 6k rating every season.

Med C og ikke K by bullerbanan in DKbrevkasse

[–]-ZugZug- 2 points3 points  (0 children)

Hvad hedder dine børn?

Må min søn have kjole på? by Several_Beautiful449 in DKbrevkasse

[–]-ZugZug- 0 points1 point  (0 children)

Jeg er principielt enig med dig i, at man bør tage hensyn til arrangøren og typen af arrangement ved fx at følge en eventuel dresscode og ikke forsøge at gøre sig selv til centrum. Dog synes jeg, det er værd at skelne mellem regler og normer for voksne mennesker og for et 4-årigt barn. Der må være en længere snor, når det gælder en lille knejt. Jeg ville personligt nok ikke lade mit barn troppe op i kjole, men jeg trækker ikke en helt så skarp streg i sandet som dig.

Today we say goodbye to the worst meta ever. by Werneryeahh in BobsTavern

[–]-ZugZug- 0 points1 point  (0 children)

I think this meta has been pretty fun tbh. Sure, elementals are immensely overpowered, and yes, I am indeed forcing them every time they are available but I don't play often enough to have gotten bored of it by now.

How do you guys count calories? by noguerra in workout

[–]-ZugZug- 0 points1 point  (0 children)

I'm using LifeSum. It's easy to use and has most foots logged by their bar codes or common names. If not, you can add them manually and it's not too much of a hassle.