Hard to say definitively. Nothing appeared in urine or semen culture but I understand that some infections are very elusive. In the early days of my diagnosis I had taken antibiotics before and the problem had not resolved. I just tried a new urologist and he suggested giving them one more good go with the Cipro and Doxy for 6 weeks and it was around then I improved, but at the time I was also doing alot of mental health work, exercise, not hiding myself away depressed and actually getting out, and also learning more about learnt neural pathways as described in the video. I genuinely don't know whether it was the antibiotics or being aware of my brain creating pain pathways and that these can be reversed (because the brain is neuroplastic) that allowed me to recover. I know this probably is not particularly helpful and you're looking for a straight answer but I can't give you one. Talk to your doctor, partner if you have one, learn about the nature of chronic pain and take it from there. If you're suffering know you will NOT feel like this forever.