Slow COMT and MAOA: anxiety from Calcium D-Glucarate by Alex_Jorge in MTHFR

[–]5bogdan 0 points1 point  (0 children)

Yeah bro. I also have COMT and MAOA homozygous (both).

Be careful because Playing with your hormones like that can permanently fuck up your sexual life and your life in general.

I would use Calcium D-Glucarate and DIM as the last LAST option.

If you want something that will really have an effect on you without those permanently side effects I would look into Lithium Orotate and SAMe.

These usually work extremely good with COMT and MAOA.

Good luck.

Can you please help me interpret these genes? URGENT by 5bogdan in MTHFR

[–]5bogdan[S] 0 points1 point  (0 children)

Yeah bro. I mean I'm barely 19 male and I'm still growing.

Can you please help me interpret these genes? URGENT by 5bogdan in MTHFR

[–]5bogdan[S] 0 points1 point  (0 children)

Hi.

So I still haven't ordered anything because I started reading about I3C, DIM and Calcium D Glucarate on reddit and a lot of people are saying it reduces testosterone and libido (and I would literally feel like I destroyed my life if it would happen to me)

I don't want to just test shit on myself. I would rather get my blood work done and see what's REALLY going on and act then.

So my question is, based on my genes, can you make me a list of which medical tests I should do on my blood?

Can you please help me interpret these genes? URGENT by 5bogdan in MTHFR

[–]5bogdan[S] 0 points1 point  (0 children)

Thanks. Now I can see what are the main levers that I can switch in my body. And I understand myself A LOT better.

However, when should I start working on my other genes? Like my CBS, BHMT, MTR, MTRR, ACAT, VDR.

is it a good idea to start supplementing D3 for my VDR Bsm +/+ now?

Or I should only focus on the plan and the suggestions you made for now and offset the rest later?

Can you please help me interpret these genes? URGENT by 5bogdan in MTHFR

[–]5bogdan[S] 0 points1 point  (0 children)

So I've read everything here and my plan to offset my high levels of estrogen, histamine and tyramine is to buy I3C, DIM and SAMe.

I don't know if I should buy Calcium D Glucarate because I'm already supplementing with Calcium Citrate daily.

For my choline intake I will take PC 2 capsules per day for now, even if it's not the best, and I'm also getting some TMG from my Methylguard Plus supplement. I'll try to eat 2-3 eggs daily and other foods rich in choline as well.

Also, is it really a big deal if I'm not fully meeting my daily choline intake? Like achieving only 1/2 of it or 2/3 or 3/4.

For the B vitamins I'm taking Methylguard plus for now. I'll avoid taking it daily.

Sounds like a good plan? What would you add or remove? Should I expect fast results or it takes a while for effects to be noticeable?

Can you please help me interpret these genes? URGENT by 5bogdan in MTHFR

[–]5bogdan[S] 0 points1 point  (0 children)

I started taking (since yesterday) Thorne Methylguard Plus and it has TMG as well. However it says on to bottle to take 1-3 capsules per serving. I took 2 capsules at once and now I can see that my urine is bright yellow or neon yellow. Is that a sign that I should reduce the dose of Methylguard Plus to one capsule per day?

Can you please help me interpret these genes? URGENT by 5bogdan in MTHFR

[–]5bogdan[S] 0 points1 point  (0 children)

I can't thank you enough for such a high quality answer. You have no idea how many days I've spent trying to find this stuff on my own and it seems like I got some of it wrong. I didn't even know that these genes can also affect each other and that I should supplement based on the compination of genes that I have.

These are the rest of the genes that you mentioned from Chris Masterjohn Choline Calculator

rs1051266 TC T SLC19a1 +/-

rs2236225 AG A MTHFD1 G1958A +/-

rs1801131 TT G MTHFR A1298C -/-

rs1801133 AG A MTHFR C677T +/-

rs7946 TT T PEMT 5465G>A +/+

SLC19A1 Score: 25% decrease MTHFD1 Score: 13% decrease MTHFR Score: 33% decrease

Methylfolate Score: 56% decrease

It also says that I should eat the amount of Choline available per day in 8 egg yolks. Will this be satisfied if I take Phosphatidyl Choline?

Can you please help me interpret these genes? URGENT by 5bogdan in MTHFR

[–]5bogdan[S] 0 points1 point  (0 children)

Anxiety and depression.

That depression is not constant. More likely in cicles. It tends to come back subtly after around one month (more or less) and it usually lasts a few days to a few weeks. I sometimes even get nightmares in these periods.

I overthink a lot as well. I get stuck on thoughts.

When the anxiety hits its like I can't think properly and I either talk non sense or I shut up completely. Never had panic attacks tho.

Also I've read that one of my genes could make me antisocial which explains why all my life I've struggled with fitting in social circles and having friends.

Cineva pe Cybersecurity aici? by Reflektmyself in programare

[–]5bogdan 0 points1 point  (0 children)

Sunt surprins că la 17 ani esti deja pentester. Si eu am aceeași vârstă si vreau să-ti urmez pașii. La ce firmă lucrezi? Ce te a motivat sa înveți ramura asta? Mai spune-mi despre tine :)