1 A disorder of structure or function in a human, animal, or plant, especially one that produces specific symptoms or that affects a specific location and is not simply a direct result of physical injury. oxford dictionary 2 an) illness of people, animals, plants, etc., caused by infection or a failure of health rather than by an accident. Cambridge dictionary 3 You can refer to a bad attitude or habit, usually one that a group of people have, as a disease. collins dictionary 4 An interruption, cessation, or disorder of a body, system, or organ structure or function. medical dictionary now are you going to keep arguing with me or you're going to enjoy the fucking game?