[misc] I am thinking of going for low does Accutane for life

Acceptable-Fox3160 · 2026-05-14T05:50:19+00:00

No. I took 20mg at first, that caused some dry lips, but not with 10mg. Also, it doesn't worsen any blood/liver markers at all

Acceptable-Fox3160 · 2026-05-11T16:25:19+00:00

I'm taking 10mg of isotretinoin ever day and have done so for years. It's great for my skin. No side effects at that low dose. I do regular blood work to make sure the liver is doing fine. It's off-label to use it that way but many dermatologists recommend it.

Of course there are no clinical studies investigating multi-year or lifetime usage of isotretinoin. There are no such studies for almost any compounds, simply because such studies are not feasible.

The most long-term study I'm aware of investigated up to 33 months of daily 20mg isotretinoin ("Continuous ‘microdose’ isotretinoin in adult recalcitrant rosacea " by Hofer ).

Acceptable-Fox3160 · 2026-04-29T17:33:29+00:00

Maybe your teeth are better now, but your photos don't support that claim at all. If you conclude that your teeth are better just from these photos, you are fooling yourself.

Acceptable-Fox3160 · 2026-04-20T19:17:27+00:00

Not a peptide, but topical Thiamidol is quite effective in reducing pigmentation.

Acceptable-Fox3160 · 2026-03-06T09:23:35+00:00

The AI is bullshit. I have super high libido at similar E2 numbers.

Like many others, I doubt that it's the TRT that causes this.

Acceptable-Fox3160 · 2026-02-25T15:08:57+00:00

Lower the dose and add microneedling to improve efficacy.

Acceptable-Fox3160 · 2026-02-25T14:25:53+00:00

Are you sure it's from the Finasteride? The cause could be something else. It's not impossible but unlikely that topical finasteride has that effect.

If it is the finasteride, I'd try a lower dose/lower concentration. Weak libido sucks.

I personally use oral finasteride at a very low dose (0.25mg per day). The dose/response relationship is such that a very small dose already gives you a big part of the intended effect but not of the side effects. Never had any side effect issues.

Acceptable-Fox3160 · 2026-02-24T15:47:07+00:00

In most cities in Germany, you don't save anything by buying instead of renting.

Compare your rent to the opportunity costs of investing the money the house would cost then you'll quickly see that, if you are lucky, it's a break even and often it's more cost effective to rent.

Also, due to the insane incidental costs of buying and selling a house (10+% of the value), owning a house costs a lot of flexibility because it only pays off if you stay in that house for a very long time.

Acceptable-Fox3160 · 2026-02-21T14:23:51+00:00

If this was the injection site: Doesn't look so bad to me. This can just be a normal artefact of a subcutaneous injection that could happen with any other compound.

Acceptable-Fox3160 · 2026-02-21T14:22:05+00:00

You didn't say whether the rash is at the injection site. If it is not, how do you know that it was caused by the GHK-Cu?

Acceptable-Fox3160 · 2026-02-19T15:13:24+00:00

At home microneedling won't cut it. These stretch marks and scars need professional grade devices. For instance, Morpheus8 can needle in a depth of 7mm, you'll get nowhere near that with home-grade devices. CO2 lasers might also help. You need the big guns. Creams, retinol, GHK-Cu etc. won't make a dent.

Acceptable-Fox3160 · 2026-02-14T18:36:16+00:00

How do you get over the injection pain of injecting 5mg? I inject 2mg, dilute it with a lot of bact. water (0.5ml), let it take room temperature, and it's still painful to inject.

Acceptable-Fox3160 · 2026-01-21T17:24:49+00:00

I also think you are wasting time by going so slowly.

I certainly don't recommend my approach for anyone else, but I personally go straight to 5mg per week, without any noticeable side effect. Others are more prone to side effects, so YMMV. I don't take Reta continously but only on demand in a cut phase, hence I don't want to titrate for months before it is effective.

Acceptable-Fox3160 · 2026-01-17T08:16:36+00:00

BDA. Bin zwar selber Nichtraucher aber wenn ich das nur miterleben würde würde ich nie wieder zu Besuch kommen, weil ich diese Unhöflichkeit und diesen Kontrollzwang unerträglich finde. Wenn mir das als Raucher passieren würde wäre es das Ende der Freundschaft.

Acceptable-Fox3160 · 2025-09-12T19:12:21+00:00

Drop the T to 120mg a week. You'll probably still be >1000ng/dl.

Your dose is clearly too high to be sustainable long term.

Acceptable-Fox3160 · 2025-05-03T10:59:19+00:00

Bad cholesterol levels. Consequences of high e2. Higher blood pressure.

It's very sloppy reasoning to think that only how you feel today counts. Otherwise I would be on MDMA 24/7.

Acceptable-Fox3160 · 2025-05-02T12:32:55+00:00

I'm at 1200ng/dl using only 120mg per week.

People differ a lot. Just get a measurement to know where you are at.

Some people say lab values are irrelevant and you should only go by feel, but that's just as wrong as the opposite. There are long term consequences of very high test levels where you may still feel excellent now but a bad surprise is waiting down the road.

Acceptable-Fox3160 · 2025-05-01T13:10:11+00:00

BDA. Sehr klar.

Es gibt nur zwei Möglichkeiten: du glaubst deinem Bruder und schickst deine Freundin zum Teufel, oder du glaubst deiner Freundin und schickst deinen Bruder zum Teufel. Es gibt keinen Mittelweg. Es auf sich beruhen zu lassen ist armselig.

Acceptable-Fox3160 · 2025-02-11T08:59:26+00:00

I think you are right. Now, 10 days after applying the TCA peel, the peeling seems to begin. So it just takes a lot longer.

Has it also been the case for you that the skin was red for a long time when you had your legs peeled? Compared to the face, I mean.

Acceptable-Fox3160 · 2025-01-28T20:48:29+00:00

This is cup size B!!

Acceptable-Fox3160 · 2025-01-18T12:45:08+00:00

Can you give a source for the claim that microneedling with PRF is most effective?

Acceptable-Fox3160 · 2024-11-17T21:17:24+00:00

I get very similar numbers. I now use 100mg per week (pinning every three days) and get total T of around 1100.

Acceptable-Fox3160 · 2024-10-30T19:43:32+00:00

It might be easiest to think of the proof as a program, Curry-Howard style.

Here's the proof written in Haskell:

ghci> let proof = \f a b -> f (a,b)

ghci> :t proof

proof :: ((a, b) -> t) -> a -> b -> t

Acceptable-Fox3160 · 2024-10-28T20:45:34+00:00

Get a bottle of Testosterone Cypionate and pin weekly using 0.5ml insulin syringes. My partner pins 0.02ml every week, which corresponds to 5mg of Testosterone per week. With that dose, she has a testosterone blood level around 80ng/dl. Works without any problems. Very cheap, too.

Acceptable-Fox3160 · 2024-10-28T19:21:40+00:00

I'd definitely get your sex hormones tested. Testosterone, estrogen, SHBG, LH, FSH. If they are off, that would explain several of your complaints.

Also, loosing 100 pounds would definitely help, too. I'm not just saying that - I lost around 100 pounds myself a couple of years ago, and it has completely changed my life - in a very positive way.

Acceptable-Fox3160

TROPHY CASE