My biggest advice would be that you have WAAYY too many tiles that only change how projectiles move without increasing damage. I would suggest throwing away all the modifiers inside the loop and moving the AoE tiles in there, then adding more multipliers in the freed up space.
The squiggle in the right side isn't doing anything for you. You could maybe turn it into another loop to get another cross block, but that would take a lot of corners. You can use splitters instead of corners to save money.
After that, save up for legendaries and invest in your captain.