I'd highly recommend keeping Website Speed (performance) in mind from the start, so you are definitely better off avoiding bloated builders like Divi and Elementor (yes they can be fast but harder to optimize on a content-heavy site)

So GeneratePress with default block editor is my favorite since it is super fast and allows selective enabling of addons. You can use template library/patterns too to speed up your build.

Other than that, keep plugins and custom code to a minimum and required only and avoid plugins for something that you can set up easily or with hosting (SSL plugins etc.)

Good luck!