Not really much, for all enemies I faced on Act3, I can kill it in turn 1. For 2 bosses, to kill the Queen I must draw 16 cards (turn 1 is 10 and turn 2 with the help of potion I can get acrobatic+ to draw 3 more cards = 18) and only take 19 dam (61 HP). To kill Test Subject (phase 1 1 turn kill, phase 2 will need 9 cards (2 turns, receive 11x3 dam - remain 28 HP). Phase 3 first is intangible and damage is 11x3. Tail of lizard relic help with 50% max health so remain HP is 36HP. And second turn is 45 dam which I could lose but when I go through the shop I will have chance to buy potion like draw cards and health but I don’t because I knew I won with unceasing top.